The N-glycosylation of immunoglobulin G as a novel biomarker of Parkinson's disease
AC Russell, M Šimurina, MT Garcia, M Novokmet… - …, 2017 - academic.oup.com
The use of the emerging “omics” technologies for large scale population screening is promising
in terms of predictive, preventive and personalized medicine. For Parkinson's disease, it …
in terms of predictive, preventive and personalized medicine. For Parkinson's disease, it …
Glycosylation of immunoglobulin G associates with clinical features of inflammatory bowel diseases
Background and Aims Causes of inflammatory bowel diseases are not well understood and
the most prominent forms, Crohn’s disease (CD) and ulcerative colitis (UC), are sometimes …
the most prominent forms, Crohn’s disease (CD) and ulcerative colitis (UC), are sometimes …
IgG glycan patterns are associated with type 2 diabetes in independent European populations
…, M Vilaj, D Urda, F Agakov, M Šimurina… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background Type 2 diabetes results from interplay between genetic and acquired factors.
Glycans on proteins reflect genetic, metabolic and environmental factors. However, …
Glycans on proteins reflect genetic, metabolic and environmental factors. However, …
Plasma N-glycan signatures are associated with features of inflammatory bowel diseases
…, M Vilaj, M Pezer, G Razdorov, M Šimurina… - Gastroenterology, 2018 - Elsevier
Background & Aims Biomarkers are needed for early detection of Crohn’s disease (CD) and
ulcerative colitis (UC) or to predict patient outcomes. Glycosylation is a common and …
ulcerative colitis (UC) or to predict patient outcomes. Glycosylation is a common and …
Glycosylation profile of IgG in moderate kidney dysfunction
Glycans constitute the most abundant and diverse form of the post-translational modifications,
and animal studies have suggested the involvement of IgG glycosylation in mechanisms of …
and animal studies have suggested the involvement of IgG glycosylation in mechanisms of …
Defining the genetic control of human blood plasma N-glycome using genome-wide association study
…, G Thareja, AS Shadrina, M Simurina… - Human molecular …, 2019 - academic.oup.com
Glycosylation is a common post-translational modification of proteins. Glycosylation is
associated with a number of human diseases. Defining genetic factors altering glycosylation may …
associated with a number of human diseases. Defining genetic factors altering glycosylation may …
[HTML][HTML] Global variability of the human IgG glycome
Immunoglobulin G (IgG) is the most abundant serum antibody which structural characteristics
and effector functions are modulated through the attachment of various sugar moieties …
and effector functions are modulated through the attachment of various sugar moieties …
[HTML][HTML] Promoter methylation of the MGAT3 and BACH2 genes correlates with the composition of the immunoglobulin G glycome in inflammatory bowel disease
…, NT Ventham, I Trbojević-Akmačić, M Šimurina… - Clinical …, 2018 - Springer
Background Many genome- and epigenome-wide association studies (GWAS and EWAS)
and studies of promoter methylation of candidate genes for inflammatory bowel disease (IBD) …
and studies of promoter methylation of candidate genes for inflammatory bowel disease (IBD) …
[HTML][HTML] IgG glycosylation and DNA methylation are interconnected with smoking
Background Glycosylation is one of the most common post-translation modifications with
large influences on protein structure and function. The effector function of immunoglobulin G (…
large influences on protein structure and function. The effector function of immunoglobulin G (…
Heritability of Human Plasma N-Glycome
The N-glycosylation profile of total human plasma proteins could be a useful biomarker for
various pathological states. Reliable high-throughput methods for such profiling have been …
various pathological states. Reliable high-throughput methods for such profiling have been …