Human periodontal ligament fibroblasts are the optimal cell source for induced pluripotent stem cells
Y Nomura, M Ishikawa, Y Yashiro… - Histochemistry and cell …, 2012 - Springer
Among the various kinds of fibroblasts existing in the human body, the periodontal ligament (PDL)
fibroblasts have been suggested as multipotent cells. Periodontal ligament fibroblasts …
fibroblasts have been suggested as multipotent cells. Periodontal ligament fibroblasts …
[HTML][HTML] Role of β-adrenergic signaling in masseter muscle
A Ito, Y Ohnuki, K Suita, M Ishikawa, Y Mototani… - PLoS …, 2019 - journals.plos.org
In skeletal muscle, the major isoform of β-adrenergic receptor (β-AR) is β 2 -AR and the minor
isoform is β 1 -AR, which is opposite to the situation in cardiac muscle. Despite extensive …
isoform is β 1 -AR, which is opposite to the situation in cardiac muscle. Despite extensive …
HSPA1A is upregulated in periodontal ligament at early stage of tooth movement in rats
C Arai, Y Nomura, M Ishikawa, K Noda, JW Choi… - Histochemistry and cell …, 2010 - Springer
Heat shock proteins (HSPs) are molecular chaperones that maintain intracellular protein
homeostasis and ensure survival of cells. Continuous orthodontic force on the tooth is …
homeostasis and ensure survival of cells. Continuous orthodontic force on the tooth is …
[HTML][HTML] Effects of chronic Porphyromonas gingivalis lipopolysaccharide infusion on skeletal muscles in mice
…, Y Ohnuki, I Matsuo, K Suita, M Ishikawa… - The journal of …, 2019 - Springer
Periodontitis, which is caused by various oral organisms, predominantly affects adults, and
is one of the main causes of tooth loss, as well as leading to progression of numerous …
is one of the main causes of tooth loss, as well as leading to progression of numerous …
[HTML][HTML] Early diagnosis of aortic calcification through dental X-ray examination for dental pulp stones
M Ishikawa, H Kanzaki, R Kodera, T Sekimizu… - Scientific Reports, 2023 - nature.com
Vascular calcification, an ectopic calcification exacerbated by aging and renal dysfunction,
is closely associated with cardiovascular disease. However, early detection indicators are …
is closely associated with cardiovascular disease. However, early detection indicators are …
[HTML][HTML] Effects of the angiotensin-converting enzyme inhibitor captopril on occlusal-disharmony-induced cardiac dysfunction in mice
A Ito, Y Ohnuki, K Suita, I Matsuo, M Ishikawa… - Scientific Reports, 2023 - nature.com
Occlusal disharmony is known to affect not only the oral cavity environment, but also the
autonomic nervous system in the heart. Since the renin-angiotensin system (RAS) inhibitor …
autonomic nervous system in the heart. Since the renin-angiotensin system (RAS) inhibitor …
[HTML][HTML] Role of TLR4 signaling on Porphyromonas gingivalis LPS-induced cardiac dysfunction in mice
I Matsuo, N Kawamura, Y Ohnuki, K Suita, M Ishikawa… - Plos one, 2022 - journals.plos.org
Oral infections, particularly periodontitis, are a well-established risk factor for cardiovascular
diseases, although the molecular mechanisms involved remain elusive. The aims of the …
diseases, although the molecular mechanisms involved remain elusive. The aims of the …
[HTML][HTML] Effects of occlusal disharmony on cardiac fibrosis, myocyte apoptosis and myocyte oxidative DNA damage in mice
Y Yagisawa, K Suita, Y Ohnuki, M Ishikawa… - PLoS …, 2020 - journals.plos.org
Occlusal disharmony leads to morphological changes in the hippocampus and osteopenia of
the lumbar vertebra and long bones in mice, and causes stress. Various types of stress are …
the lumbar vertebra and long bones in mice, and causes stress. Various types of stress are …
[HTML][HTML] Oral angiotensin-converting enzyme inhibitor captopril protects the heart from Porphyromonas gingivalis LPS-induced cardiac dysfunction in mice
K Kiyomoto, I Matsuo, K Suita, Y Ohnuki, M Ishikawa… - Plos one, 2023 - journals.plos.org
Although angiotensin converting enzyme (ACE) inhibitors are considered useful for the
treatment of human heart failure, some experimental failing-heart models have shown little …
treatment of human heart failure, some experimental failing-heart models have shown little …
Effects of chronic Porphylomonas gingivalis lipopolysaccharide infusion on cardiac dysfunction in mice
I Matsuo, Y Ohnuki, K Suita, M Ishikawa… - Journal of Oral …, 2021 - Elsevier
Objective Periodontitis (PD) is a chronic inflammatory disease of tooth-supportive tissue. An
association between PD and cardiovascular disease (CVD) has been established. Although …
association between PD and cardiovascular disease (CVD) has been established. Although …