Detection of disease-associated, cell-free nucleic acids in body fluids enables early diagnostics,
genotyping and personalized therapy, but is challenged by the low concentrations of …

Comprehensive molecular analysis of rare circulating tumor cells (CTCs) and cell clusters is
often hampered by low throughput and purity, as well as cell loss. To address this, we …

Objectives A malignant pleural effusion (MPE) is a common complication in non-small cell
lung cancer (NSCLC) with important staging and prognostic information. Patients with MPEs …

Dear Editor, Malignant pleural effusions (MPE) in advanced nonsmall-cell lung cancer (NSCLC)
offer a rich source of tumour-derived material for liquid biopsy. 1 However, molecular …

Circulating tumor cells (CTCs) carry valuable biological information. While enumeration of
CTCs in peripheral blood is an FDA‐approved prognostic indicator of survival in metastatic …

Barrett’s esophagus (BE) is metaplasia of the squamous epithelium to a specialized columnar
epithelium. BE progresses through low-and high-grade dysplasia before developing into …

ABSTRACT Characterization of disease-associated, cell-free nucleic acids (liquid biopsy)
provides a powerful, minimally-invasive means for early disease detection, genotyping, and …

Correction: Flow based single cell analysis of the immune landscape distinguishes Barrett’s
esophagus from adjacent normal tissue - PMC Back to Top Skip to main content NIH NLM Logo …

Noninvasive isolation of circulating tumor cells (CTCs) from patient blood samples allows for
interrogation of valuable molecular and phenotypic information useful for disease diagnosis …

Full-length TCR and BCR analysis with single-cell multiomic assays provides an
understanding of immune responses, offering insights into the complete receptor structure and …