User profiles for Mofolusho Falade
Mofolusho FaladeProfessor of Biology, Transylvania University Verified email at transy.edu Cited by 915 |
In vivo antimalarial and cytotoxic properties of Annona senegalensis extract
The in vivo animal antimalarial and in vitro cytotoxic activities of the methanol extract of Annona
senegalensis Pers.(Annonaceae) was investigated in this study. The in vivo antimalarial …
senegalensis Pers.(Annonaceae) was investigated in this study. The in vivo antimalarial …
Current treatment and drug discovery against Leishmania spp. and Plasmodium spp.: a review
Malaria and leishmaniasis are the most prevalent tropical diseases caused by protozoan
parasites. Half of world's population is at risk of malaria and more than 2 million of new cases of …
parasites. Half of world's population is at risk of malaria and more than 2 million of new cases of …
In vitro antiplasmodial activity and toxicity assessment of some plants from Nigerian ethnomedicine
…, E Ajaiyeoba, T Happi, M Falade… - Pharmaceutical …, 2011 - Taylor & Francis
Context: The emergence and spread of Plasmodium falciparum-resistant parasites to nearly
all available antimalarial drugs pose a threat to malaria control and necessitates the need to …
all available antimalarial drugs pose a threat to malaria control and necessitates the need to …
[HTML][HTML] Analysis of antibiotics resistant genes in different strains of Staphylococcus aureus
B Otarigho, MO Falade - Bioinformation, 2018 - ncbi.nlm.nih.gov
The control of Staphylococcus aureus infection is being hampered by methicillin and other
resistant strains. The identification of the unique antibiotic resistant genes from the genomes …
resistant strains. The identification of the unique antibiotic resistant genes from the genomes …
Synthesis and Structure–Activity Relationship of Dual-Stage Antimalarial Pyrazolo[3,4-b]pyridines
Malaria remains one of the most deadly infectious diseases, causing hundreds of thousands
of deaths each year, primarily in young children and pregnant mothers. Here, we report the …
of deaths each year, primarily in young children and pregnant mothers. Here, we report the …
Molecular identification, in vivo and in vitro activities of Calvatia gigantea (macro-fungus) as an antidiabetic agent
Mushrooms are cherished as sources of food, nutrients and medicine. Inadequate data on
the identity and medicinal properties of many wild Nigerian mushrooms has limited their …
the identity and medicinal properties of many wild Nigerian mushrooms has limited their …
[HTML][HTML] Computational Screening of Approved Drugs for Inhibition of the Antibiotic Resistance Gene mecA in Methicillin-Resistant Staphylococcus aureus (MRSA) …
B Otarigho, MO Falade - BioTech, 2023 - mdpi.com
Antibiotic resistance is a critical problem that results in a high morbidity and mortality rate.
The process of discovering new chemotherapy and antibiotics is challenging, expensive, and …
The process of discovering new chemotherapy and antibiotics is challenging, expensive, and …
[HTML][HTML] DNA barcoding of Clarias gariepinus, Coptodon zillii and Sarotherodon melanotheron from Southwestern Nigeria
DNA barcoding has been adopted as a gold standard rapid, precise and unifying identification
system for animal species and provides a database of genetic sequences that can be …
system for animal species and provides a database of genetic sequences that can be …
[HTML][HTML] Antimalarial activity of tetrahydro-β-carbolines targeting the ATP binding pocket of the Plasmodium falciparum heat shock 90 protein
…, MJ Walls, S Durham, DR Pillai, MO Falade… - Bioorganic & medicinal …, 2020 - Elsevier
A series of tetrahydro-β-carboline derivatives of a lead compound known to target the heat
shock 90 protein of Plasmodium falciparum were synthesized and assayed for both potency …
shock 90 protein of Plasmodium falciparum were synthesized and assayed for both potency …
[PDF][PDF] Plasmodium para-aminobenzoate synthesis and salvage resolve avoidance of folate competition and adaptation to host diet
Folate metabolism is essential for DNA synthesis and a validated drug target in fast-growing
cell populations, including tumors and malaria parasites. Genome data suggest that …
cell populations, including tumors and malaria parasites. Genome data suggest that …