Background With the rise in fluoroquinolone-resistant Salmonella Typhi and the recent
emergence of ceftriaxone resistance, azithromycin is one of the last oral drugs available against …

Background Precise enteric fever disease burden data are needed to inform prevention and
control measures, including the use of newly available typhoid vaccines. We established the …

Typhoid fever, caused by Salmonella enterica serovar Typhi, is a global public health concern
due to increasing antimicrobial resistance (AMR). Characterization of S. Typhi genomes …

The rising prevalence of antimicrobial resistance in Salmonella enterica serovars Typhi and
Paratyphi A, causative agents of typhoid and paratyphoid, have led to fears of untreatable …

Salmonella Paratyphi A, the primary etiology of paratyphoid, is estimated to cause 3.4
million infections annually, worldwide. With rising antimicrobial resistance and no licensed …

With prequalification of a typhoid conjugate vaccine by the World Health Organization,
countries are deciding whether and at what geographic scale to provide the vaccine. Optimal …

Background Typhoid and paratyphoid remain common bloodstream infections in areas with
suboptimal water and sanitation infrastructure. Paratyphoid, caused by Salmonella …

Background Salmonella enterica serovar Paratyphi A (Salmonella Paratyphi A) is the primary
causative agent of paratyphoid fever, which is responsible for an estimated 3.4 million …

Background Sensitivity of culture for the detection of Streptococcus pneumoniae is limited by
prior antibiotic exposure. Immunochromatographic test (ICT) is highly sensitive and specific …

Background. Rising antimicrobial resistance (AMR) in Salmonella Typhi restricts typhoid
treatment options, heightening concerns for pan-oral drug-resistant outbreaks. Bangladesh …