User profiles for Molly McDougle

Molly McDougle

Postdoctoral Fellow, Florida State University
Verified email at fsu.edu
Cited by 297

Central and peripheral GLP-1 systems independently suppress eating

…, MK Holt, A Singh, A de Araujo, M McDougle… - Nature …, 2021 - nature.com
The anorexigenic peptide glucagon-like peptide-1 (GLP-1) is secreted from gut
enteroendocrine cells and brain preproglucagon (PPG) neurons, which, respectively, define the …

[PDF][PDF] Separate gut-brain circuits for fat and sugar reinforcement combine to promote overeating

M McDougle, A de Araujo, A Singh, M Yang, I Braga… - Cell metabolism, 2024 - cell.com
Food is a powerful natural reinforcer that guides feeding decisions. The vagus nerve conveys
internal sensory information from the gut to the brain about nutritional value; however, the …

Role for the rostromedial tegmental nucleus in signaling the aversive properties of alcohol

EJ Glover, MJ McDougle, GS Siegel… - Alcoholism: Clinical …, 2016 - Wiley Online Library
Background While the rewarding effects of alcohol contribute significantly to its addictive
potential, it is becoming increasingly appreciated that alcohol's aversive properties also play an …

Intact vagal gut‐brain signalling prevents hyperphagia and excessive weight gain in response to high‐fat high‐sugar diet

M McDougle, D Quinn, C Diepenbroek… - Acta …, 2021 - Wiley Online Library
Aim The tools that have been used to assess the function of the vagus nerve lack specificity.
This could explain discrepancies about the role of vagal gut‐brain signalling in long‐term …

Dorsal striatum dopamine oscillations: Setting the pace of food anticipatory activity

G de Lartigue, M McDougle - Acta Physiologica, 2019 - Wiley Online Library
Predicting the uncertainties of the ever‐changing environment provides a competitive
advantage for animals. The need to anticipate food sources has provided a strong evolutionary …

[PDF][PDF] Blunted vagal cocaine-and amphetamine-regulated transcript promotes hyperphagia and weight gain

SJ Lee, JP Krieger, M Vergara, D Quinn, M McDougle… - Cell reports, 2020 - cell.com
The vagus nerve conveys gastrointestinal cues to the brain to control eating behavior. In
obesity, vagally mediated gut-brain signaling is disrupted. Here, we show that the cocaine- and …

Labeled lines for fat and sugar reward combine to promote overeating

M McDougle, A de Araujo, M Vergara, M Yang, A Singh… - bioRxiv, 2022 - biorxiv.org
Food is a powerful natural reinforcer that guides feeding decisions. The vagus nerve conveys
internal sensory information from the gut to the brain about nutritional value; however, the …

[HTML][HTML] Asymmetric control of food intake by left and right vagal sensory neurons

AM de Araujo, I Braga, G Leme, A Singh, M McDougle… - BioRxiv, 2023 - ncbi.nlm.nih.gov
We investigated the lateralization of gut-innervating vagal sensory neurons and their roles
in feeding behavior. Using genetic, anatomical, and behavioral analyses, we discovered a …

Separate orexigenic hippocampal ensembles shape dietary choice by enhancing contextual memory and motivation

M Yang, A Singh, MJ McDougle, L Decarie-Spain… - bioRxiv, 2023 - biorxiv.org
The hippocampus (HPC), traditionally known for its role in learning and memory, has emerged
as a controller of food intake. While prior studies primarily associated the HPC with food …

Fats and Sugars Recruit Distinct Gut‐Brain Circuits To Control Food Intake And Reward

M McDougle, A de Araujo, M Vergara… - The FASEB …, 2022 - Wiley Online Library
The high‐fat high‐sugar food environment has been implicated as a driver of the obesity
epidemic. Nodose ganglia (NG) neurons transmit post‐ingestive signals, including fat and …