User profiles for Monica Aguilera

Monica Aguilera

Professor Asociado
Verified email at udl.cat
Cited by 805

[PDF][PDF] VarSome: the human genomic variant search engine

…, A Kouris, CE Chapple, M Albarca Aguilera… - …, 2019 - academic.oup.com
VarSome.com is a search engine, aggregator and impact analysis tool for human genetic
variation and a community-driven project aiming at sharing global expertise on human variants…

[HTML][HTML] The impact of western diet and nutrients on the microbiota and immune response at mucosal interfaces

D Statovci, M Aguilera, J MacSharry… - Frontiers in …, 2017 - frontiersin.org
Recent findings point toward diet having a major impact on human health. Diets can either
affect the gut microbiota resulting in alterations in the host’s physiological responses or by …

[PDF][PDF] Identity noise and adipogenic traits characterize dermal fibroblast aging

…, FO Peixoto, CSO Attolini, N Prats, M Aguilera… - Cell, 2018 - cell.com
During aging, stromal functions are thought to be impaired, but little is known whether this
stems from changes of fibroblasts. Using population- and single-cell transcriptomics, as well …

Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

…, RG Urdinguio, A Berenguer‐Llergo, M Aguilera… - Aging …, 2022 - Wiley Online Library
The expression of the pluripotency factors OCT4, SOX2, KLF4, and MYC (OSKM) can
convert somatic differentiated cells into pluripotent stem cells in a process known as …

Vertical sheep mobility along the altitudinal gradient through stable isotope analyses in tooth molar bioapatite, meteoric water and pastures: A reference from the Ebro …

C Tornero, M Aguilera, JP Ferrio, H Arcusa… - Quaternary …, 2018 - Elsevier
Although the frequency of pastoral activities involving vertical sheep mobility has decreased
over the last century, this is a herding strategy still used in the Ebro basin, where animals …

A retrospective, dual‐isotope approach reveals individual predispositions to winter‐drought induced tree dieback in the southernmost distribution limit of S cots pine

…, JJ Camarero, D Carulla, M Aguilera… - Plant, Cell & …, 2013 - Wiley Online Library
Winter‐drought induced forest diebacks in the low‐latitude margins of species' distribution
ranges can provide new insights into the mechanisms (carbon starvation, hydraulic failure) …

A genome editing approach to study cancer stem cells in human tumors

…, M Sevillano, M Aguilera… - EMBO molecular …, 2017 - embopress.org
The analysis of stem cell hierarchies in human cancers has been hampered by the impossibility
of identifying or tracking tumor cell populations in an intact environment. To overcome …

Stable carbon and nitrogen isotopes and quality traits of fossil cereal grains provide clues on sustainability at the beginnings of Mediterranean agriculture

M Aguilera, JL Araus, J Voltas… - … Journal Devoted to …, 2008 - Wiley Online Library
We present a novel approach to study the sustainability of ancient Mediterranean agriculture
that combines the measurement of carbon isotope discrimination (Δ 13 C) and nitrogen …

[HTML][HTML] Agronomic conditions and crop evolution in ancient Near East agriculture

JL Araus, JP Ferrio, J Voltas, M Aguilera… - Nature …, 2014 - nature.com
The appearance of agriculture in the Fertile Crescent propelled the development of Western
civilization. Here we investigate the evolution of agronomic conditions in this region by …

[HTML][HTML] The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2

…, A García-Garijo, K Meyer, MI Muñoz, M Aguilera… - Nature Cancer, 2024 - nature.com
Chemotherapy often generates intratumoral senescent cancer cells that strongly modify the
tumor microenvironment, favoring immunosuppression and tumor growth. We discovered, …