Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation
T H 17 lymphocytes appear to be essential in the pathogenesis of numerous inflammatory
diseases. We demonstrate here the expression of IL-17 and IL-22 receptors on blood-brain …
diseases. We demonstrate here the expression of IL-17 and IL-22 receptors on blood-brain …
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence
…, M Sabbagh, K Wosik, L Bourbonnière, M Bernard… - Science, 2011 - science.org
The blood-brain barrier (BBB) is composed of tightly bound endothelial cells (ECs) and
perivascular astrocytes that regulate central nervous system (CNS) homeostasis. We showed …
perivascular astrocytes that regulate central nervous system (CNS) homeostasis. We showed …
Preferential recruitment of interferon‐γ–expressing TH17 cells in multiple sclerosis
Objective There is substantial evidence supporting the role of interferon (IFN)‐γ–producing T
helper (T H ) 1 and interleukin (IL)‐17–expressing T H 17 lymphocytes in multiple sclerosis (…
helper (T H ) 1 and interleukin (IL)‐17–expressing T H 17 lymphocytes in multiple sclerosis (…
Angiotensin II controls occludin function and is required for blood–brain barrier maintenance: relevance to multiple sclerosis
…, F Berthelet, M Bernard… - Journal of …, 2007 - Soc Neuroscience
The blood–brain barrier (BBB) restricts molecular and cellular trafficking between the blood
and the CNS. Although astrocytes are known to control BBB permeability, the molecular …
and the CNS. Although astrocytes are known to control BBB permeability, the molecular …
The blood–brain barrier induces differentiation of migrating monocytes into Th17-polarizing dendritic cells
Trafficking of antigen-presenting cells into the CNS is essential for lymphocyte reactivation
within the CNS compartment. Although perivascular dendritic cells found in inflammatory …
within the CNS compartment. Although perivascular dendritic cells found in inflammatory …
Effects of bariatric surgery on cardiac ectopic fat: lesser decrease in epicardial fat compared to visceral fat loss and no change in myocardial triglyceride content
…, MC Alessi, K Clément, M Bernard… - Journal of the American …, 2012 - jacc.org
Objectives : This study investigated the effect of bariatric surgery (BS)–induced weight loss
on cardiac ectopic fat using 3T magnetic resonance imaging in morbid obesity. Background : …
on cardiac ectopic fat using 3T magnetic resonance imaging in morbid obesity. Background : …
Statins reduce human blood–brain barrier permeability and restrict leukocyte migration: relevance to multiple sclerosis
Objective Dysregulation of the blood–brain barrier (BBB) and transendothelial migration of
immune cells are among the earliest central nervous system changes partaking in lesion …
immune cells are among the earliest central nervous system changes partaking in lesion …
Phospholipid fingerprints of milk from different mammalians determined by 31P NMR: Towards specific interest in human health
…, S Confort-Gouny, PJ Cozzone, M Armand, M Bernard - Food Chemistry, 2012 - Elsevier
Our objective was to identify and quantify phospholipids in milk from different species (human
HM, cow CoM, camel CaM, and mare MM) using an optimised 31 P NMR spectroscopy …
HM, cow CoM, camel CaM, and mare MM) using an optimised 31 P NMR spectroscopy …
[HTML][HTML] Effect of empagliflozin on ectopic fat stores and myocardial energetics in type 2 diabetes: the EMPACEF study
…, Y Lefur, L Pini, S Rapacchi, M Bernard… - Cardiovascular …, 2021 - Springer
Background Empagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that has
demonstrated cardiovascular and renal protection in patients with type 2 diabetes (T2D). We …
demonstrated cardiovascular and renal protection in patients with type 2 diabetes (T2D). We …
Vitamin D protects against diet-induced obesity by enhancing fatty acid oxidation
Prospective studies reported an inverse correlation between 25-hydroxyvitamin D [25(OH)D]
plasma levels and prevalence of obesity and type 2 diabetes. In addition, 25(OH)D status …
plasma levels and prevalence of obesity and type 2 diabetes. In addition, 25(OH)D status …