[HTML][HTML] Guidelines for laboratory diagnosis of coronavirus disease 2019 (COVID-19) in Korea

…, JS Kim, HS Kim, ST Lee, MW Seong… - Annals of laboratory …, 2020 - ncbi.nlm.nih.gov
The outbreak of coronavirus disease 2019 (COVID-19), which began in December 2019, is
still ongoing in Korea, with> 9,000 confirmed cases as of March 25, 2020. COVID-19 is a …

[HTML][HTML] Molecular basis and diagnosis of thalassemia

JS Lee, S Im Cho, SS Park, MW Seong - Blood research, 2021 - ncbi.nlm.nih.gov
Thalassemia is characterized by the impaired synthesis of globin chains due to disease-causing
variants in α-or β-globin genes. In this review, we provide an overview of the molecular …

[HTML][HTML] Virus isolation from the first patient with SARS-CoV-2 in Korea

…, JY Kim, J Yun, GW Lee, MW Seong… - Journal of Korean …, 2020 - ncbi.nlm.nih.gov
Novel coronavirus (SARS-CoV-2) is found to cause a large outbreak started from Wuhan
since December 2019 in China and SARS-CoV-2 infections have been reported with …

[HTML][HTML] Viral RNA load in mildly symptomatic and asymptomatic children with COVID-19, Seoul, South Korea

MS Han, MW Seong, N Kim, S Shin… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
Along with positive SARS-CoV-2 RNA in nasopharyngeal swabs, viral RNA was detectable
at high concentration for> 3 weeks in fecal samples from 12 mildly symptomatic and …

[HTML][HTML] Recent progress in laboratory diagnosis of thalassemia and hemoglobinopathy: a study by the Korean Red Blood Cell Disorder Working Party of the Korean …

…, HJ Kim, K Lee, SH Park, SH Song, MW Seong… - Blood …, 2019 - ncbi.nlm.nih.gov
Genetic hemoglobin disorders are caused by mutations and/or deletions in the α-globin or β-globin
genes. Thalassemia is caused by quantitative defects and hemoglobinopathies by …

[HTML][HTML] Tumor infiltrating PD1-positive lymphocytes and the expression of PD-L1 predict poor prognosis of soft tissue sarcomas

JR Kim, YJ Moon, KS Kwon, JS Bae, S Wagle, KM Kim… - PloS one, 2013 - journals.plos.org
Recently, the possibility of PD1 pathway-targeted therapy has been extensively studied in
various human malignant tumors. However, no previous study has investigated their potential …

Tumor-infiltrating PD1-positive lymphocytes and FoxP3-positive regulatory T cells predict distant metastatic relapse and survival of clear cell renal cell carcinoma

MJ Kang, KM Kim, JS Bae, HS Park, H Lee… - Translational …, 2013 - Elsevier
BACKGROUND: Clear cell renal cell carcinoma (CRCC) is the most common malignant tumor
of the kidney, and the clinical outcome of CRCC is related with the metastatic potential of …

Evidence of severe acute respiratory syndrome coronavirus 2 reinfection after recovery from mild coronavirus disease 2019

…, BS Chin, WB Park, SS Park, MW Seong - Clinical Infectious …, 2021 - academic.oup.com
Background Positive results from real-time reverse-transcription polymerase chain reaction (rRT-PCR)
in recovered patients raise concern that patients who recover from coronavirus …

Overexpression of SIRT1 protects pancreatic β-cells against cytokine toxicity by suppressing the nuclear factor-κB signaling pathway

JH Lee, MY Song, EK Song, EK Kim, WS Moon… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE—SIRT1, a class III histone/protein deacetylase, is known to interfere with the
nuclear factor-κB (NF-κB) signaling pathway and thereby has an anti-inflammatory function. …

Pharmacokinetics and tolerance of the phage endolysin-based candidate drug SAL200 after a single intravenous administration among healthy volunteers

…, K Jang, KS Yu, JY Cho, MW Seong… - Antimicrobial agents …, 2017 - Am Soc Microbiol
This study was a phase 1, single-center, randomized, double-blind, placebo-controlled,
single-dosing, and dose-escalating study of intravenous SAL200. It is a new candidate drug for …