The main physiological actions of the biologically most active metabolite of vitamin D, 1α,25-dihydroxyvitamin
D 3 (1α,25(OH) 2 D 3 ), are calcium and phosphorus uptake and transport …

Over the last 25 years roles have been established for vitamin D receptor (VDR) in influencing
cell proliferation and differentiation. For example, murine knock-out approaches have …

The Vitamin D-activating enzyme 25-hydroxyvitamin D-1α-hydroxylase (1α-hydroxylase) is
now known to be expressed in a much wider range of tissues that previously thought, …

We completed a multicenter study of the effects of pomegranate cold-pressed (Oil) or
supercritical CO 2 -extracted (S) seed oil, fermented juice polyphenols (W), and pericarp …

We investigated whether dissimilar biochemical fractions originating in anatomically discrete
sections of the pomegranate (Punica granatum) fruit might act synergistically against …

The main regulator of the human tumor suppresser gene p21 (waf1/cip1) is the transcription
factor p53, but more recently it has been suggested to be a primary anti-proliferative target …

Purpose: Vitamin D seems to exert a protective effect against common cancers, although this
does not correlate with circulating levels of active 1,25-dihydroxyvitamin D 3 [1,25(OH) 2 D …

KDM6B/JMJD3 is a histone H3 lysine demethylase with an important gene regulatory role in
development and physiology. Here, we show that human JMJD3 expression is induced by …

Vitamin D from the diet or synthesized in the skin upon UV-B irradiation is converted in the
organism into the active metabolite 1α,25- dihydroxyvitamin D 3 [1,25(OH) 2 D 3 , calcitriol], a …

The process of DNA CpG methylation has been extensively investigated for over 50 years
and revealed associations between changing methylation status of CpG islands and gene …