The genetic basis of autism spectrum disorder (ASD) is known to consist of contributions from
de novo mutations in variant-intolerant genes. We hypothesize that rare inherited structural …

Fetal alcohol spectrum disorders (FASDs) are characterized by life-long changes in gene
expression, neurodevelopment and behavior. What mechanisms initiate and maintain these …

Fetal alcohol spectrum disorders (FASD) remain the most common preventable cause of
behavioural abnormalities and cognitive deficits, yet little is known about the biological …

Background Maternal alcohol consumption is known to adversely affect fetal neurodevelopment.
While it is known that alcohol dose and timing play a role in the cognitive and …

There is abundant evidence that prenatal alcohol exposure leads to a range of behavioral
and cognitive impairments, categorized under the term fetal alcohol spectrum disorders (…

Many women continue to consume low to moderate quantities of alcohol during pregnancy,
which can result in the variable neurobehavioural effects in the absence of physiological …

Background Prenatal alcohol exposure is known to result in fetal alcohol spectrum disorders,
a continuum of physiological, behavioural, and cognitive phenotypes that include …

The developing brain is remarkably sensitive to alcohol exposure, resulting in the wide range
of cognitive and neurobehavioral characteristics categorized under the term fetal alcohol …

The Spsb family of genes encode well-conserved proteins of unknown function. Mammalian
Spsb genes are likely the result of three separate duplication and divergence events during …

Most familial behavioral phenotypes result from the complex interaction of multiple genes.
Studies of such phenotypes involving human subjects are often inconclusive owing to …