RNA sequencing (RNA-seq) is the leading technology for genome-wide transcript quantification.
However, publicly available RNA-seq data is currently provided mostly in raw form, a …

The Library of Integrated Network-Based Cellular Signatures (LINCS) is an NIH Common
Fund program that catalogs how human cells globally respond to chemical, genetic, and …

While gene expression data at the mRNA level can be globally and accurately measured,
profiling the activity of cell signaling pathways is currently much more difficult. …

As more digital resources are produced by the research community, it is becoming
increasingly important to harmonize and organize them for synergistic utilization. The findable, …

Mechanistic molecular studies in biomedical research often discover important genes that are
aberrantly over- or under-expressed in disease. However, manipulating these genes in an …

… This study showed that 13 C solid state NMR coupled with 13 C selective labeling and peak
deconvolution analysis is a very powerful method for analyzing the local structure of SF and …

We report on an experimental study of the role of mode of delivery and pregnancy on the
architecture of vaginal elastic fibers and vaginal vault elasticity in female Sprague-Dawley rats. …

Elastin, the principal component of the elastic fiber of the extracellular matrix, imparts to
vertebrate tissues remarkable resilience and longevity. This work focuses on elucidating …

As more datasets, tools, workflows, APIs, and other digital resources are produced by the
research community, it is becoming increasingly difficult to harmonize and organize these …

Elastin is a protein of the extracellular matrix that contributes significantly to the elasticity of
connective tissues. In this study, we examine dynamical and structural modifications of aortic …