We here analyze data from the first year of an ongoing nationwide program of genetic
surveillance of Plasmodium falciparum parasites in Senegal. The analysis is based on 1097 …

Individuals with acute malaria infection generated high levels of antibodies that cross-react
with the SARS-CoV-2 Spike protein. Cross-reactive antibodies specifically recognized the …

In 2006, Senegal adopted artemisinin-based combination therapy (ACT) as first-line treatment
in the management of uncomplicated malaria. This study aimed to update the status of …

Dengue virus is a major and rapidly growing public health concern in tropic and subtropic
regions across the globe. In late 2018, Senegal experienced its largest dengue virus outbreak …

Background The use of artemisinin as a monotherapy resulted in the emergence of artemisinin
resistance in 2005 in Southeast Asia. Monitoring of artemisinin combination therapy (ACT…

Multiple-strain (polygenomic) infections are a ubiquitous feature of Plasmodium falciparum
parasite population genetics. Under simple assumptions of superinfection, polygenomic …

The worldwide decline in malaria incidence is revealing the extensive burden of non-malarial
febrile illness (NMFI), which remains poorly understood and difficult to diagnose. To …

Molecular epidemiology using genomic data can help identify relationships between malaria
parasite population structure, malaria transmission intensity, and ultimately help generate …

Background In 2006, the Senegalese National Malaria Control Programme recommended
artemisinin-based combination therapy (ACT) with artemether–lumefantrine as the first-line …

Sero-surveillance can monitor and project disease burden and risk. However, SARS-CoV-2
antibody test results can produce false positive results, limiting their efficacy as a sero-…