User profiles for Mudan He
 | Mudan HeInsititute of Hydrobiology, CAS Verified email at ihb.ac.cn Cited by 308 |
[HTML][HTML] Induced formation of primordial germ cells from zebrafish blastomeres by germplasm factors
…, J Zhu, H Wang, W Deng, S Jiao, Y Wang, M He… - Nature …, 2023 - nature.com
The combination of genome editing and primordial germ cell (PGC) transplantation has
enormous significance in the study of developmental biology and genetic breeding, despite its …
enormous significance in the study of developmental biology and genetic breeding, despite its …
[HTML][HTML] Abundance of early embryonic primordial germ cells promotes zebrafish female differentiation as revealed by lifetime labeling of germline
…, L Zhu, Q Zhang, F Xiong, H Wang, X Wang, M He… - Marine …, 2019 - Springer
Teleost sex differentiation largely depends on the number of undifferentiated germ cells. Here,
we describe the generation and characterization of a novel transgenic zebrafish line, Tg(…
we describe the generation and characterization of a novel transgenic zebrafish line, Tg(…
Surrogate production of genome-edited sperm from a different subfamily by spermatogonial stem cell transplantation
…, X Li, Y Li, D Ye, R Zhang, X Wang, M He… - Science China Life …, 2022 - Springer
The surrogate reproduction technique, such as inter-specific spermatogonial stem cells (SSCs)
transplantation (SSCT), provides a powerful tool for production of gametes derived from …
transplantation (SSCT), provides a powerful tool for production of gametes derived from …
Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9
…, Z Zhu, A Meng, L Pan, H Wang, W Xie, M He… - Genome …, 2020 - genome.cshlp.org
Genome editing by the well-established CRISPR/Cas9 technology has greatly facilitated
our understanding of many biological processes. However, a complete whole-genome …
our understanding of many biological processes. However, a complete whole-genome …
Cyp11a2 Is Essential for Oocyte Development and Spermatogonial Stem Cell Differentiation in Zebrafish
Cytochrome P45011A1, encoded by Cyp11a1, converts cholesterol to pregnenolone (P5),
the first and rate-limiting step in steroidogenesis. In zebrafish, cyp11a1 is maternally …
the first and rate-limiting step in steroidogenesis. In zebrafish, cyp11a1 is maternally …
[HTML][HTML] The release of tryptase from mast cells promote tumor cell metastasis via exosomes
H Xiao, M He, G Xie, Y Liu, Y Zhao, X Ye, X Li, M Zhang - BMC cancer, 2019 - Springer
Background Cancer cells release exosomes and can be taken up by mast cells (MCs), but
the potential functional effects of MCs on tumor metastasis remain unknown. Method …
the potential functional effects of MCs on tumor metastasis remain unknown. Method …
Efficient generation of zebrafish maternal-zygotic mutants through transplantation of ectopically induced and Cas9/gRNA targeted primordial germ cells
The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 technology
has been widely utilized for knocking out genes involved in various biological processes in …
has been widely utilized for knocking out genes involved in various biological processes in …
Translational control by maternal Nanog promotes oogenesis and early embryonic development
Many maternal mRNAs are translationally repressed during oocyte development and spatio-temporally
activated during early embryogenesis, which is crucial for oocyte and early …
activated during early embryogenesis, which is crucial for oocyte and early …
[HTML][HTML] The combination of CTCs and CEA can help guide the management of patients with SPNs suspected of being lung cancer
J Zheng, X Ye, Y Liu, Y Zhao, M He, H Xiao - BMC cancer, 2020 - Springer
Objective Solitary pulmonary nodules (SPNs) is a common radiographic finding and require
further evaluation because of the possibility of lung cancer. This study aimed to determine …
further evaluation because of the possibility of lung cancer. This study aimed to determine …
Elovl2 but not Elovl5 is essential for the biosynthesis of docosahexaenoic acid (DHA) in zebrafish: insight from a comparative gene knockout study
Teleost fish can synthesize one of the major omega-3 long-chain polyunsaturated fatty
acids (n-3 LC-PUFAs), docosahexaenoic acid (DHA, 22:6n-3), from dietary α-linolenic acid (ALA; …
acids (n-3 LC-PUFAs), docosahexaenoic acid (DHA, 22:6n-3), from dietary α-linolenic acid (ALA; …