In humans, the ability to digest lactose, the sugar in milk, declines after weaning because of
decreasing levels of the enzyme lactase-phlorizin hydrolase, encoded by LCT. However, …

Cancer chemotherapy resistance (MDR) is the innate and/or acquired ability of cancer cells
to evade the effects of chemotherapeutics and is one of the most pressing major dilemmas in …

Helicobacter pylori (HP) is a facultative anaerobic bacterium. HP is a normal flora having
immuno-modulating properties. This bacterium is an example of a microorganism inducing …

Binary polymorphisms associated with the non-recombining region of the human Y
chromosome (NRY) preserve the paternal genetic legacy of our species that has persisted to the …

A SNP in the gene encoding lactase (LCT) (C/T-13910) is associated with the ability to
digest milk as adults (lactase persistence) in Europeans, but the genetic basis of lactase …

Africa is the source of all modern humans, but characterization of genetic variation and of
relationships among populations across the continent has been enigmatic. We studied 121 …

We study the major levels of Y‐chromosome haplogroup variation in 15 Sudanese populations
by typing major Y‐haplogroups in 445 unrelated males representing the three linguistic …

We report a genome-wide association (GWA) study of severe malaria in The Gambia. The
initial GWA scan included 2,500 children genotyped on the Affymetrix 500K GeneChip, and a …

Slc11a1 (formerly Nramp1) has many pleiotropic effects on macrophage (m) activation,
including regulation of the CXC chemokine KC, interleukin-1β (IL-1β), inducible nitric oxide …

Cancer cells acquire an unusual glycolytic behavior relative, to a large extent, to their intracellular
alkaline pH (pH i). This effect is part of the metabolic alterations found in most, if not all, …