Axon regeneration in the central nervous system normally fails, in part because of a developmental
decline in the intrinsic ability of CNS projection neurons to extend axons. Members of …

The brain communicates with the spinal cord through numerous axon tracts that arise from
discrete nuclei, transmit distinct functions, and often collateralize to facilitate the coordination …

Although ubiquitous in biological studies, the enhanced green and yellow fluorescent
proteins (EGFP and EYFP) were not specifically optimized for neuroscience, and their …

Neurons in the central nervous system (CNS) lose their ability to regenerate early in
development, but the underlying mechanisms are unknown. By screening genes developmentally …

To restore function after injury to the CNS, axons must be stimulated to extend into denervated
territory and, critically, must form functional synapses with appropriate targets. We showed …

Embryonic neurons, peripheral neurons, and CNS neurons in zebrafish respond to axon injury
by initiating pro-regenerative transcriptional programs that enable axons to extend, locate …

Neurons in the central nervous system lose their intrinsic capacity for axon regeneration as
they mature, and it is widely hypothesized that changes in gene expression are responsible. …

We used aerial photographs to measure long‐term loss of forest cover in dry to mesic forests
at Pu'u Wa'aWa'a on the island of Hawai'i. The aerial extent of dense forest decreased 62 …

Neurons in the adult mammalian CNS decrease in intrinsic axon growth capacity during
development in concert with changes in Krüppel-like transcription factors (KLFs). KLFs regulate …

Daily and annual changes in light are processed by central clock circuits that control the
timing of behavior and physiology. The suprachiasmatic nucleus (SCN) in the anterior …