We found that the cancerous pancreas harbors a markedly more abundant microbiome
compared with normal pancreas in both mice and humans, and select bacteria are differentially …

Background Human papillomavirus (HPV) infection is one of the most common sexually
transmitted infections. However, only a small percentage of high-risk (HR) HPV infections …

Objective Tryptophan can be catabolised to various metabolites through host kynurenine
and microbial indole pathways. We aimed to examine relationships of host and microbial …

Background: Integrated microbiome and metabolomics analyses hold the potential to reveal
interactions between host and microbiota in relation to disease risks. However, there are …

Background Hispanics living in the USA may have unrecognized potential birthplace and
lifestyle influences on the gut microbiome. We report a cross-sectional analysis of 1674 …

Studies of the human microbiome frequently omit characterization of fungal communities (the
mycobiome), which limits our ability to investigate how fungal communities influence …

Background Immune checkpoint blockade (ICB) shows lasting benefits in advanced melanoma;
however, not all patients respond to this treatment and many develop potentially life-…

Background Alterations in gut microbiota have been implicated in HIV infection and
cardiovascular disease. However, how gut microbial alterations relate to host inflammation and …

Bacterial vaginosis (BV) is a highly prevalent condition that is associated with adverse health
outcomes. It has been proposed that BV’s role as a pathogenic condition is mediated via …

Menopause is a pivotal period during which loss of ovarian hormones increases
cardiometabolic risk and may also influence the gut microbiome. However, the menopause-microbiome …