Dental caries and periodontitis account for a vast burden of morbidity and healthcare
spending, yet their genetic basis remains largely uncharacterized. Here, we identify self-reported …

Genome-wide association scans of complex multipartite traits like the human face typically
use preselected phenotypic measures. Here we report a data-driven approach to …

Numerous lines of evidence point to a genetic basis for facial morphology in humans, yet little
is known about how specific genetic variants relate to the phenotypic expression of many …

Background Over 90% of adults aged 20 years or older with permanent teeth have suffered
from dental caries leading to pain, infection, or even tooth loss. Although caries prevalence …

The human face is complex and multipartite, and characterization of its genetic architecture
remains challenging. Using a multivariate genome-wide association study meta-analysis of …

Several studies have now shown evidence of association between common genetic variants
and quantitative facial traits in humans. The reported associations generally involve simple …

The etiology of chronic periodontitis clearly includes a heritable component. Our purpose was
to perform a small exploratory genome-wide association study in adults ages 18–49 years …

The human face represents a combined set of highly heritable phenotypes, but knowledge
on its genetic architecture remains limited, despite the relevance for various fields. A series of …

Context: Prenatal exposure to phthalates disrupts male sex development in rodents. In humans,
the placental glycoprotein hormone human chorionic gonadotropin (hCG) is required for …

There is increasing evidence that genetic risk variants for non-syndromic cleft lip/palate (nsCL/P)
are also associated with normal-range variation in facial morphology. However, …