User profiles for N. E. Davey
Norman E. DaveyInstitute Of Cancer Research, London Verified email at icr.ac.uk Cited by 12380 |
[PDF][PDF] A million peptide motifs for the molecular biologist
A molecular description of functional modules in the cell is the focus of many high-throughput
studies in the postgenomic era. A large portion of biomolecular interactions in virtually all …
studies in the postgenomic era. A large portion of biomolecular interactions in virtually all …
Short linear motifs: ubiquitous and functionally diverse protein interaction modules directing cell regulation
The eukaryotic cell is a bustling collection of macromolecules acting cooperatively to mediate
the functions required for cell viability. Specific, context-dependent and tightly controlled …
the functions required for cell viability. Specific, context-dependent and tightly controlled …
How viruses hijack cell regulation
Viruses, as obligate intracellular parasites, are the pathogens that have the most intimate
relationship with their host, and as such, their genomes have been shaped directly by …
relationship with their host, and as such, their genomes have been shaped directly by …
[HTML][HTML] Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
…, R Horos, BM Beckmann, C Strein, NE Davey… - Cell, 2012 - cell.com
RNA-binding proteins (RBPs) determine RNA fate from synthesis to decay. Employing two
complementary protocols for covalent UV crosslinking of RBPs to RNA, we describe a …
complementary protocols for covalent UV crosslinking of RBPs to RNA, we describe a …
[HTML][HTML] A structural biology community assessment of AlphaFold2 applications
Most proteins fold into 3D structures that determine how they function and orchestrate the
biological processes of the cell. Recent developments in computational methods for protein …
biological processes of the cell. Recent developments in computational methods for protein …
Attributes of short linear motifs
NE Davey, K Van Roey, RJ Weatheritt, G Toedt… - Molecular …, 2012 - pubs.rsc.org
Traditionally, protein–protein interactions were thought to be mediated by large, structured
domains. However, it has become clear that the interactome comprises a wide range of …
domains. However, it has become clear that the interactome comprises a wide range of …
The eukaryotic linear motif resource: 2022 release
…, N Farahi, M Käser, R Kraleti, NE Davey… - Nucleic acids …, 2022 - academic.oup.com
Almost twenty years after its initial release, the Eukaryotic Linear Motif (ELM) resource
remains an invaluable source of information for the study of motif-mediated protein-protein …
remains an invaluable source of information for the study of motif-mediated protein-protein …
The eukaryotic linear motif resource ELM: 10 years and counting
…, K Van Roey, S Michael, NE Davey… - Nucleic acids …, 2014 - academic.oup.com
The eukaryotic linear motif (ELM http://elm.eu.org ) resource is a hub for collecting, classifying
and curating information about short linear motifs (SLiMs). For >10 years, this resource has …
and curating information about short linear motifs (SLiMs). For >10 years, this resource has …
ELM—the database of eukaryotic linear motifs
…, S Michael, RJ Weatheritt, NE Davey… - Nucleic acids …, 2012 - academic.oup.com
Linear motifs are short, evolutionarily plastic components of regulatory proteins and provide
low-affinity interaction interfaces. These compact modules play central roles in mediating …
low-affinity interaction interfaces. These compact modules play central roles in mediating …
MobiDB: intrinsically disordered proteins in 2021
The MobiDB database (URL: https://mobidb.org/ ) provides predictions and annotations for
intrinsically disordered proteins. Here, we report recent developments implemented in …
intrinsically disordered proteins. Here, we report recent developments implemented in …