p300/CBP and cancer
p300 and cyclic AMP response element-binding protein (CBP) are adenoviral E1A-binding
proteins involved in multiple cellular processes, and function as transcriptional co-factors and …
proteins involved in multiple cellular processes, and function as transcriptional co-factors and …
Safety recommendations for evaluation and surgery of the head and neck during the COVID-19 pandemic
…, SB Chinn, D Clayburgh, NG Iyer… - … –head & neck …, 2020 - jamanetwork.com
Importance The rapidly expanding novel coronavirus disease 2019 (COVID-19) pandemic,
caused by severe acute respiratory syndrome coronavirus 2, has challenged the medical …
caused by severe acute respiratory syndrome coronavirus 2, has challenged the medical …
Novel therapeutic targets on the horizon for lung cancer
Lung cancer is a leading cause of cancer-related mortality worldwide, and is classically
divided into two major histological subtypes: non-small-cell lung cancer (NSCLC) and small-cell …
divided into two major histological subtypes: non-small-cell lung cancer (NSCLC) and small-cell …
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
… We used 100 ng of cDNA for PCR amplification and amplified all of the sequences with
multiple cycle numbers (20–35 cycles) to determine the appropriate conditions for identifying …
multiple cycle numbers (20–35 cycles) to determine the appropriate conditions for identifying …
Changing epidemiology of oral squamous cell carcinoma of the tongue: a global study
Background There are reports about the changing epidemiology of tongue squamous cell
carcinoma (SCC), with recent reports indicating an increasing incidence in young women. …
carcinoma (SCC), with recent reports indicating an increasing incidence in young women. …
The mutational landscape of adenoid cystic carcinoma
…, MA Leversha, CE Rice, B Singh, NG Iyer… - Nature …, 2013 - nature.com
… Approximately 300 ng of RNA was extracted from fresh-frozen tissue, and RNA integrity
was assessed using the Eukaryote Total RNA Nano Assay on the Agilent 2100 Bioanalyzer. …
was assessed using the Eukaryote Total RNA Nano Assay on the Agilent 2100 Bioanalyzer. …
Rising incidence of second cancers in patients with low‐risk (T1N0) thyroid cancer who receive radioactive iodine therapy
NG Iyer, LGT Morris, RM Tuttle, AR Shaha, I Ganly - Cancer, 2011 - Wiley Online Library
BACKGROUND: American Thyroid Association guidelines currently recommend the selective
use of radioactive iodine (RAI) therapy in patients with well differentiated thyroid cancer (…
use of radioactive iodine (RAI) therapy in patients with well differentiated thyroid cancer (…
Randomized trial comparing surgery and adjuvant radiotherapy versus concurrent chemoradiotherapy in patients with advanced, nonmetastatic squamous cell …
BACKGROUND The current study was performed to report the long‐term results of a trial
comparing concurrent chemotherapy and radiotherapy (CCRT) with surgery and adjuvant …
comparing concurrent chemotherapy and radiotherapy (CCRT) with surgery and adjuvant …
[HTML][HTML] The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel
…, J Temple, C Blenkiron, M Vias, CE Massie, NG Iyer… - Cancer cell, 2007 - cell.com
The extracellular matrix (ECM) can induce chemotherapy resistance via AKT-mediated
inhibition of apoptosis. Here, we show that loss of the ECM protein TGFBI (transforming growth …
inhibition of apoptosis. Here, we show that loss of the ECM protein TGFBI (transforming growth …
[HTML][HTML] Recommendations for head and neck surgical oncology practice in a setting of acute severe resource constraint during the COVID-19 pandemic: an …
…, W Golusiński, A Homma, S Hosal, NG Iyer… - The Lancet …, 2020 - thelancet.com
The speed and scale of the global COVID-19 pandemic has resulted in unprecedented
pressures on health services worldwide, requiring new methods of service delivery during the …
pressures on health services worldwide, requiring new methods of service delivery during the …