Kawasaki disease (KD) is a pediatric vasculitis that damages the coronary arteries in 25% of
untreated and approximately 5% of treated children. Epidemiologic data suggest that KD is …

The COVID-19 pandemic has led to an exponential increase in SARS-CoV-2 infections and
associated deaths, and represents a significant challenge to healthcare professionals and …

Patients with mutations in AICDA, which encodes activation-induced cytidine deaminase (AID),
display an impaired peripheral B cell tolerance. AID mediates class-switch recombination …

Astellas, MSD, Novartis, Tillotts Pharma, and Biose; grants from Biocodex, Danone, and
BiomX; and is a co-founder of Exeliom Biosciences. JK and EJK report grants from Vedanta …

Kawasaki disease is a systemic vasculitis of unknown etiology, with clinical observations
suggesting a substantial genetic contribution to disease susceptibility. We conducted a genome…

Refractive errors are the most common ocular disorders worldwide and may lead to
blindness. Although this trait is highly heritable, identification of susceptibility genes has been …

Epidemic C. difficile (027/BI/NAP1) has rapidly emerged in the past decade as the leading
cause of antibiotic-associated diarrhea worldwide. However, the key events in evolutionary …

… , 6 samples spiked at a level of 0.5 ng g −1 , 6 samples spiked at 1 ng g −1 , 6 samples
spiked at 1.5 ng g −1 , 1 sample spiked at 2 ng g −1 and 1 sample spiked at 5 ng g −1 (Fig. 2). …

… The mean fasting plasma leptin level at the end of the low-fat phase (14.5 ± 14.9 ng/mL)
was insignificantly lower than that observed at the end of the high-fat phase (15.6 ± 15.2 …

… , levels were at a median of 216 ng/ml in the first week. These … ng/ml and 156 ng/ml,
respectively. For comparison, the median level in a group of age-matched afebrile controls was 50 ng…