User profiles for N. J. Isaac
 | Nick IsaacUK Centre for Ecology & Hydrology; Centre for Ecology & Hydrology Verified email at ceh.ac.uk Cited by 17918 |
Design of a" minimAl" homeodomain: the N-terminal arm modulates DNA binding affinity and stabilizes homeodomain structure.
Z Shang, VE Isaac, H Li, L Patel… - Proceedings of the …, 1994 - National Acad Sciences
This report investigates the sequence specificity requirements for homeodomain structure
and DNA binding activity by the design and synthesis of a "minimAl" homeodomain (for …
and DNA binding activity by the design and synthesis of a "minimAl" homeodomain (for …
Regulators of mitonuclear balance link mitochondrial metabolism to mtDNA expression
Mitochondrial oxidative phosphorylation (OXPHOS) complexes are assembled from proteins
encoded by both nuclear and mitochondrial DNA. These dual-origin enzymes pose a …
encoded by both nuclear and mitochondrial DNA. These dual-origin enzymes pose a …
Joint digital signal processing receivers for spatial superchannels
…, X Zhou, SL Woodward, R Isaac… - IEEE Photonics …, 2012 - ieeexplore.ieee.org
We discuss the advantages of spatial superchannels for future terabit networks based on
space-division multiplexing (SDM), and demonstrate reception of spatial superchannels by a …
space-division multiplexing (SDM), and demonstrate reception of spatial superchannels by a …
Multicenter analysis of geriatric fitness and real-world outcomes in older patients with classical Hodgkin lymphoma
VM Orellana-Noia, K Isaac, MK Malecek… - Blood …, 2021 - ashpublications.org
We performed a multicenter retrospective analysis across 10 US academic medical centers
to evaluate treatment patterns and outcomes in patients age ≥60 years with classic Hodgkin …
to evaluate treatment patterns and outcomes in patients age ≥60 years with classic Hodgkin …
Defaunation in the Anthropocene
We live amid a global wave of anthropogenically driven biodiversity loss: species and
population extirpations and, critically, declines in local species abundance. Particularly, human …
population extirpations and, critically, declines in local species abundance. Particularly, human …
Environment and Rural Affairs Monitoring & Modelling Programme-ERAMMP Report-85 Development of Indicator 44: Status of Biological Diversity in Wales Final …
We report the development of a new indicator of the status of biological diversity for Wales:
indicator 44 for the Well-being of Future Generations (Wales) Act (2015). The focus of this …
indicator 44 for the Well-being of Future Generations (Wales) Act (2015). The focus of this …
Shortwave infrared detection of medical radioisotope Cerenkov luminescence.
… arrays (NIRVana 640 84 TE, Princeton Teledyne, NJ, USA or ZephIR 1.7x, Photon etc Inc., …
Black posterboard (TB5, Thorlabs, 93 NJ, USA) was used to absorb CL and allow γ particles …
Black posterboard (TB5, Thorlabs, 93 NJ, USA) was used to absorb CL and allow γ particles …
Implementation of an enhanced recovery pathway after pancreaticoduodenectomy in patients with low drain fluid amylase
RP Sutcliffe, M Hamoui, J Isaac… - World journal of …, 2015 - Wiley Online Library
Introduction The safety and feasibility of an enhanced recovery pathway (ERP) after pancreatic
surgery is largely unknown. Our aim was to prospectively evaluate a targeted ERP after …
surgery is largely unknown. Our aim was to prospectively evaluate a targeted ERP after …
[HTML][HTML] Recent advances in engineered nanoparticles for RNAi-mediated crop protection against insect pests
Since the discovery of RNA interference (RNAi) in the nematode worm Caenorhabditis
elegans in 1998 by Fire and Mello et al., strides have been made in exploiting RNAi for …
elegans in 1998 by Fire and Mello et al., strides have been made in exploiting RNAi for …
Protection of Double-Stranded RNA via Complexation with Double Hydrophilic Block Copolymers: Influence of Neutral Block Length in Biologically Relevant …
CE Pugsley, RE Isaac, NJ Warren, JS Behra… - …, 2022 - ACS Publications
Interaction between the anionic phosphodiester backbone of DNA/RNA and polycations can
be exploited as a means of delivering genetic material for therapeutic and agrochemical …
be exploited as a means of delivering genetic material for therapeutic and agrochemical …