… Nandakumar Narayanan is a physician-scientist who is interested in the circuitry of
neuropsychiatric disease. In the lab, he studies how dopamine influences prefrontal networks that …

Recent evidence has emerged demonstrating that metabolic hormones such as ghrelin and
leptin can act on ventral tegmental area (VTA) midbrain dopamine neurons to influence …

Introduction The involvement of dopaminergic neurons in the ventral tegmental area (VTA)
in Parkinson’s disease (PD) has not been universally recognized by neuroscientists and …

Dorsomedial prefrontal cortex is critical for the temporal control of behavior. Dorsomedial
prefrontal cortex might alter neuronal activity in areas such as motor cortex to inhibit temporally …

In this report we describe how common brain networks within the medial frontal cortex (MFC)
facilitate adaptive behavioral control in rodents and humans. We demonstrate that after …

Neuroimaging studies have been inconclusive in characterizing the role of the prefrontal
cortex (PFC) for maintaining increasingly larger amounts of information in working memory (WM…

Muscimol is a GABA A -agonist that causes rapid and reversible suppression of neurophysiological
activity. Interpretations of the effects of muscimol infusions into the brain have been …

Parkinson’s disease (PD) is a common neurodegenerative disease that lacks therapies to
prevent progressive neurodegeneration. Impaired energy metabolism and reduced ATP levels …

In simple reaction time tasks, lesions of rat dorsomedial prefrontal cortex impair the ability to
wait for trigger stimuli and result in increased premature responding. This effect could be …

Although the prefrontal cortex influences motivated behavior, its role in food intake remains
unclear. Here, we demonstrate a role for D1-type dopamine receptor–expressing neurons in …