User profiles for N. Boles
 | Nathan C. BolesNeural Stem Cell Institute Verified email at neuralsci.org Cited by 4600 |
Mouse hematopoietic stem cell identification and analysis
GA Challen, N Boles, KYK Lin… - Cytometry Part A: The …, 2009 - Wiley Online Library
Hematopoietic stem cells (HSCs) remain by far the most well‐characterized adult stem cell
population both in terms of markers for purification and assays to assess functional potential. …
population both in terms of markers for purification and assays to assess functional potential. …
[PDF][PDF] Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice
Hematopoietic stem cells (HSCs) represent one of the first recognized somatic stem cell
types. As such, nearly 200 genes have been examined for roles in HSC function in knockout …
types. As such, nearly 200 genes have been examined for roles in HSC function in knockout …
Mechanisms of stress in the brain
The brain is the central organ involved in perceiving and adapting to social and physical
stressors via multiple interacting mediators, from the cell surface to the cytoskeleton to …
stressors via multiple interacting mediators, from the cell surface to the cytoskeleton to …
Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection
Lymphocytes and neutrophils are rapidly depleted by systemic infection 1 . Progenitor cells
of the haematopoietic system, such as common myeloid progenitors and common lymphoid …
of the haematopoietic system, such as common myeloid progenitors and common lymphoid …
[PDF][PDF] Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-β1
The traditional view of hematopoiesis has been that all the cells of the peripheral blood are
the progeny of a unitary homogeneous pool of hematopoietic stem cells (HSCs). Recent …
the progeny of a unitary homogeneous pool of hematopoietic stem cells (HSCs). Recent …
[PDF][PDF] ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids
Frontotemporal dementia (FTD) because of MAPT mutation causes pathological accumulation
of tau and glutamatergic cortical neuronal death by unknown mechanisms. We used …
of tau and glutamatergic cortical neuronal death by unknown mechanisms. We used …
[PDF][PDF] Hematopoietic fingerprints: an expression database of stem cells and their progeny
SM Chambers, NC Boles, KYK Lin, MP Tierney… - Cell stem cell, 2007 - cell.com
Hematopoietic stem cells (HSCs) continuously regenerate the hematologic system, yet few
genes regulating this process have been defined. To identify candidate factors involved in …
genes regulating this process have been defined. To identify candidate factors involved in …
Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing
AV Ergen, NC Boles, MA Goodell - Blood, The Journal of the …, 2012 - ashpublications.org
… (D) Graph represents lineage distribution of donor-derived cells of Y→O vs Y→Y
transplants at 16 weeks excluding T cells (n = 4 Y→Y, n = 7 Y→O). Error bars represent SEM. …
transplants at 16 weeks excluding T cells (n = 4 Y→Y, n = 7 Y→O). Error bars represent SEM. …
[HTML][HTML] Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction
… (B) Survival percentage for 4-week-old A129 mice infected with ZIKV and treated with
temoporfin (n = 12) or vehicle (n = 10). Survival curves were compared using the Log-rank test. …
temoporfin (n = 12) or vehicle (n = 10). Survival curves were compared using the Log-rank test. …
[HTML][HTML] CORTECON: a temporal transcriptome analysis of in vitro human cerebral cortex development from human embryonic stem cells
Many neurological and psychiatric disorders affect the cerebral cortex, and a clearer
understanding of the molecular processes underlying human corticogenesis will provide greater …
understanding of the molecular processes underlying human corticogenesis will provide greater …