… b Body weight and percentage change in body weight of control (n = 13) and Piezo1 ΔEC
(n = 14) mice before and 10–14 days after tamoxifen (TAM) treatment. c As percentages of …

… Averaged data are presented as mean ± SEM, where n represents the number of independent
experiments for a given result and N indicates the total number of replicates within the …

Mechanical force is a determinant of Notch signalling but the mechanism of force detection
and its coupling to Notch are unclear. We propose a role for Piezo1 channels, which are …

Background and Purpose The protein PIEZO1 forms mechanically activated, calcium‐permeable,
non‐selective cation channels in numerous cell types from several species. Options for …

Background & Aims PIEZO1 and TRPV4 are mechanically and osmotically regulated
calcium‐permeable channels. The aim of this study was to determine the relevance and …

Rationale: A hallmark of type 2 diabetes is insulin resistance, which leads to increased
endothelial cell (EC) production of superoxide and a simultaneous reduction in the availability of …

Mechanical force has emerged as a determinant of Notch signalling but the mechanisms of
force sensing and coupling to Notch are unclear. Here we propose a role for Piezo1 channels…

… Elizabeth L Evans (joint first author), Kevin Cuthbertson (joint first author), Naima Endesh
(joint first … The right of Naima Eltuhami Endesh to be identified as Author of this work has been …