User profiles for N. Frazão

Nelson Frazao

Instituto Gulbenkian de Ciência
Verified email at igc.gulbenkian.pt
Cited by 996

Natural History of Drug-Resistant Clones of Streptococcus pneumoniae Colonizing Healthy Children in Portugal

…, S Nunes, JA Carriço, NG Sousa, N Frazão… - Microbial drug …, 2005 - liebertpub.com
… 31-CEM/NET and N. Frazão was supported by grant from IBET, project Ref. 28/12/02 CB
and from grant 011/BIC/2004 from contract LSHM-CT-2003-503413. The authors thank the …

Evolution of commensal bacteria in the intestinal tract of mice

A Sousa, N Frazão, RS Ramiro, I Gordo - Current Opinion in Microbiology, 2017 - Elsevier
Highlights • The composition of the gut microbiota is shaped by positive and negative
microbe–microbe and host-microbe interactions. • Evolution of a bacterial species in these …

Assessment of band-based similarity coefficients for automatic type and subtype classification of microbial isolates analyzed by pulsed-field gel electrophoresis

…, C Simas, S Nunes, NG Sousa, N Frazao… - Journal of Clinical …, 2005 - Am Soc Microbiol
… Nunes, NG Sousa, and N. Frazão have been supported since March 2004 by grants 010/BIC/2004, …
Simas was supported by a grant from IBET, project WLP (grant 31 CEM/NET); and N. …

[HTML][HTML] Changes in pneumococcal serotypes and antibiotypes carried by vaccinated and unvaccinated day-care centre attendees in Portugal, a country with …

R Sa-Leao, S Nunes, A Brito-Avô, N Frazao… - Clinical microbiology …, 2009 - Elsevier
The seven-valent pneumococcal conjugate vaccine (PCV7) has been available in Portugal
since June 2001, but is not included in the National Vaccination Plan. Its impact on …

Horizontal gene transfer overrides mutation in Escherichia coli colonizing the mammalian gut

N Frazão, A Sousa, M Lässig… - Proceedings of the …, 2019 - National Acad Sciences
Bacteria evolve by mutation accumulation in laboratory experiments, but tempo and mode
of evolution in natural environments are largely unknown. Here, we study the ubiquitous …

Analysis of invasiveness of pneumococcal serotypes and clones circulating in Portugal before widespread use of conjugate vaccines reveals heterogeneous behavior …

…, N Frazao, N Gonçalves-Sousa… - Journal of clinical …, 2011 - Am Soc Microbiol
… Nunes, and N. Frazão were supported by grants SFRH/BD/27518/2006, SFRH/BD/40706/2007,
and SFRH/BD/30103/2006, respectively, from Fundação para a Ciência e Tecnologia, …

Effect of the seven-valent conjugate pneumococcal vaccine on carriage and drug resistance of Streptococcus pneumoniae in healthy children attending day-care …

N Frazão, A Brito-Avô, C Simas… - The Pediatric …, 2005 - journals.lww.com
… Drs Frazão and Brito-Avô contributed equally to the work. Both are co-first authors. … The
intervention group (n = 238) included 118 male and 120 female subjects. The control group (…

Ecotype formation and prophage domestication during gut bacterial evolution

N Frazão, I Gordo - BioEssays, 2023 - Wiley Online Library
How much bacterial evolution occurs in our intestines and which factors control it are currently
burning questions. The formation of new ecotypes, some of which capable of coexisting …

[HTML][HTML] Two modes of evolution shape bacterial strain diversity in the mammalian gut for thousands of generations

N Frazão, A Konrad, M Amicone, E Seixas… - Nature …, 2022 - nature.com
How and at what pace bacteria evolve when colonizing healthy hosts remains unclear. Here,
by monitoring evolution for more than six thousand generations in the mouse gut, we show …

A multivariate approach for multi-step demand forecasting in assembly industries: Empirical evidence from an automotive supply chain

…, P Cortez, MS Carvalho, NM Frazao - Decision Support …, 2021 - Elsevier
… Suppose we are given n training observations in a set G = {(x i , y i )} i=1 n ⊂ ℝ m × ℝ,
where x i is a m–dimensional vector of input features and y i is the corresponding target output. …