Emerging viruses have the potential to impose substantial mortality, morbidity and economic
burdens on human populations. Tracking the spread of infectious diseases to assist in their …

The COVID-19 pandemic galvanized the field of virus genomic surveillance, demonstrating
its utility for public health. Now, we must harness the momentum that led to increased …

… b, Heat map comparison of the major immune cell populations within PBMCs in patients
with moderate (n = 121) or severe (n = 43) COVID-19, or HCSs (n = 43). n values represent a …

… , the impact of human behavior on WNV spread [63], specifically through the unintentional
transport of WNV-infected birds or mosquitoes via the dense trucking industry in North America…

… We obtained longitudinal serial time-point samples from a subset of these 98 study
participants (n = 48; information in Extended Data Table 1). To compare the immune phenotypes …

… In b–d, n values include longitudinal samples from the same patient. Significance in b, c
was determined using a linear mixed model with correction for multiple comparisons (Methods). …

… , n = 73 for sludge virus RNA samples, n = 75 daily positive tests by date of specimen collection,
n … of specimen collection, n = 75 daily reported hospitalizations and n = 75 daily reported …

… Using PCR, we amplified the nsp10, RdRp, nsp14, E and N genes with specifically designed
primers (Supplementary Table 2). We purified PCR products using the Mag-Bind TotalPure …

Genome sequencing has become a powerful tool for studying emerging infectious diseases;
however, genome sequencing directly from clinical samples (ie, without isolation and culture…

… a,b, Plasma reactivity to the spike (S) protein (a) and RBD (b) measured with ELISA (DR n =
101 and Yale n = 32 at each respective time point). Horizontal lines indicate the mean values…