User profiles for N. Hug
Nicolas HugIRIT, Toulouse - France Verified email at irit.fr Cited by 554 |
Mechanism and regulation of the nonsense-mediated decay pathway
N Hug, D Longman, JF Cáceres - Nucleic acids research, 2016 - academic.oup.com
The Nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs
harboring premature termination codons (PTCs) but also regulates the abundance of a large …
harboring premature termination codons (PTCs) but also regulates the abundance of a large …
Telomere length homeostasis
N Hug, J Lingner - Chromosoma, 2006 - Springer
… The crystal structure of the N-terminal half of human POT1 containing the two OB folds with
telomeric DNA oligonucleotides shows that the 3′ terminal G is buried in the protein, which …
telomeric DNA oligonucleotides shows that the 3′ terminal G is buried in the protein, which …
[PDF][PDF] Surprise: A Python library for recommender systems
N Hug - Journal of Open Source Software, 2020 - joss.theoj.org
Recommender systems aim at providing users with a list of recommendations of items that a
service offers. For example, a video streaming service will typically rely on a recommender …
service offers. For example, a video streaming service will typically rely on a recommender …
A topological mechanism for TRF2-enhanced strand invasion
…, C Faivre-Moskalenko, D Angelov, N Hug… - Nature structural & …, 2007 - nature.com
… domain and on the capacity of the C- or N-terminal part of the protein to bind DNA. … N-terminal
acidic domain. Unfortunately, we were unable to purify a mutated form of TRF1 lacking its N…
acidic domain. Unfortunately, we were unable to purify a mutated form of TRF1 lacking its N…
Ultrahigh mass activity Pt entities consisting of Pt single atoms, clusters, and nanoparticles for improved hydrogen evolution reaction
…, M Knäbbeler‐Buß, P Hügenell, S Pollitt, N Hug… - Small, 2023 - Wiley Online Library
… –N interactions between the N-functionalities of N-doped carbons and either Pt precursors [
31 ] or Pt NPs, [ 32-34 ] (or Pt clusters and single sites) where the strong Pt–N … mesoporous N-…
31 ] or Pt NPs, [ 32-34 ] (or Pt clusters and single sites) where the strong Pt–N … mesoporous N-…
[HTML][HTML] The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants
… This is in contrast to the more conventional near fully penetrant N-terminal variants 33 , seen
in most examples of pure familial CEBPA AML. DDX41 variants were detected in probands …
in most examples of pure familial CEBPA AML. DDX41 variants were detected in probands …
[HTML][HTML] Genetic variation and RNA structure regulate microRNA biogenesis
N Fernandez, RA Cordiner, RS Young, N Hug… - Nature …, 2017 - nature.com
… The red dots indicate those positions protected by SRSF3 in a dose-dependent manner (n=5).
Mann–Whitney U-test was used to evaluate differences (f) Schematic representation of the …
Mann–Whitney U-test was used to evaluate differences (f) Schematic representation of the …
DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans
D Longman, N Hug, M Keith, C Anastasaki… - Nucleic acids …, 2013 - academic.oup.com
The nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs harboring
premature termination codons but also regulates the abundance of cellular RNAs. We …
premature termination codons but also regulates the abundance of cellular RNAs. We …
[PDF][PDF] The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex
N Hug, JF Caceres - Cell reports, 2014 - cell.com
… upon depletion of UPF1 and DHX34 (n = 800), UPF2 (n = 896), or UPF3b (n = 310). We
defined … of RNA targets with UPF2 and UPF1 (n = 277) and with UPF3b and UPF1 (n = 166) …
defined … of RNA targets with UPF2 and UPF1 (n = 277) and with UPF3b and UPF1 (n = 166) …
[PDF][PDF] Analogy-preserving functions: a way to extend Boolean samples
… Also, considering that f essentially depends on n ≤ m variables (n is then the number of
αi equal to 1), f is equivalent to the function g: Bn → B defined by g(x1, ··· ,xn) = x1 + ··· + xn. …
αi equal to 1), f is equivalent to the function g: Bn → B defined by g(x1, ··· ,xn) = x1 + ··· + xn. …