Many proteins contain disordered regions of low-sequence complexity, which cause aging-associated
diseases because they are prone to aggregate. Here, we study FUS, a prion-like …

… In mature neurons (11 to 12 DIV), microtubules nucleated randomly throughout the whole
cell but did not emanate from the centrosome (n > 30 cells). In young neurons expressing the …

To the Editor: Current state-of-the-art light-sheet microscopes rely on sophisticated control
software to perform the acquisition of gigabytes of image data per second over the course of …

… The lateral (ie, on a plane perpendicular to the optical axis) resolution is similar to the
resolution that can be achieved using TIRF; however, the S/N ratio is lower compared to TIRF …

To the editor—Modern microscopy generates staggering amounts of multidimensional image
data that place increasing demands on processing flexibility and efficiency. One way to …

The use of optical tweezers to measure forces acting upon microscopic particles has
revolutionised fields from material science to cell biology. However, despite optical control …

… by attached motors, F ι = N ι f ι and F r = N r f r . Here, N ι and N r are the total number of …
The linear densities, n ι = N ι /L ι and n r = N r /L r , of the motors attached to the left and the …

… N-gTBD or N-gTBD + C-CTD at DIV1 (Figures 1H and 1I; Video S1). Interestingly, centrosomal
depletion of Cdk5rap2 by C-CTD alone caused only a small decrease in centrosomal MT …

… n signifies the number of PGCs examined in (H) or the number of embryos analyzed in (E).
Error … The zebrafish were handled according to the law of the state of North Rhine-Westphalia, …

… r p,n is the position of the nth particle and r t,n is the position of the nth target … The software
was developed by Nicola Maghelli and Sergei Klykov at MPI-CBG and further optimized …