European heart rhythm association (EHRA)/heart rhythm society (HRS)/Asia pacific heart rhythm society (APHRS)/latin American heart rhythm society (LAHRS) expert …
Purpose Genetic testing has advanced significantly since the publication of the 2011 HRS/EHRA
Expert Consensus Statement on the State of Genetic Testing for the Channelopathies …
Expert Consensus Statement on the State of Genetic Testing for the Channelopathies …
Molecular mechanism for an inherited cardiac arrhythmia
PB Bennett, K Yazawa, N Makita, AL George Jr - Nature, 1995 - nature.com
… The vertical axis was scaled to open probability (P,) by dividing the ensemble average
current by the unitary current (j) and the number of channels in the patch (N). Vertical calibration …
current by the unitary current (j) and the number of channels in the patch (N). Vertical calibration …
Cardiac connexins, mutations and arrhythmias
… Recently, Makita et al. [36▪▪] reported that a germline mutation in GJA5, the gene coding
for Cx40, also associated with PFHBI. Indeed, the authors screened 156 probands with …
for Cx40, also associated with PFHBI. Indeed, the authors screened 156 probands with …
Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II
…, Y Qin, M Sano, H Takano, T Minamino, N Makita… - Nature cell …, 2004 - nature.com
The angiotensin II type 1 (AT1) receptor has a crucial role in load-induced cardiac hypertrophy.
Here we show that the AT1 receptor can be activated by mechanical stress through an …
Here we show that the AT1 receptor can be activated by mechanical stress through an …
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death
… were excluded for batch effect: such SNPs were defined as those with significant differences
in allele frequency in one plate versus all others within cases and within controls only (n = …
in allele frequency in one plate versus all others within cases and within controls only (n = …
Tyrosine kinase inhibitor–induced thyroid disorders: a review and hypothesis
N Makita, T Iiri - Thyroid, 2013 - liebertpub.com
… versus interferon alfa in metastatic renal-cell carcinomaN Engl J Med356115124. 5. Motzer
… 37 Makita NMiyakawa MFujita TIiri T2010Sunitinib induces hypothyroidism with a markedly …
… 37 Makita NMiyakawa MFujita TIiri T2010Sunitinib induces hypothyroidism with a markedly …
Moderate Increase of Mean Daily Temperature Adversely Affects Fruit Set of Lycopersicon esculentum by Disrupting Specific Physiological Processes in Male …
S Sato, M Kamiyama, T Iwata, N Makita… - Annals of …, 2006 - academic.oup.com
• Background and Aims Global warming is gaining significance as a threat to natural and
managed ecosystems since temperature is one of the major environmental factors affecting …
managed ecosystems since temperature is one of the major environmental factors affecting …
Fibrosis, connexin-43, and conduction abnormalities in the Brugada syndrome
…, S Rothery, N Makita, S Kowase, N Boonmee… - Journal of the American …, 2015 - jacc.org
Background : The right ventricular outflow tract (RVOT) is acknowledged to be responsible
for arrhythmogenesis in Brugada syndrome (BrS), but the pathophysiology remains …
for arrhythmogenesis in Brugada syndrome (BrS), but the pathophysiology remains …
The complete nucleotide sequence and multipartite organization of the tobacco mitochondrial genome: comparative analysis of mitochondrial genomes in higher …
Y Sugiyama, Y Watase, M Nagase, N Makita… - Molecular Genetics and …, 2005 - Springer
Tobacco is a valuable model system for investigating the origin of mitochondrial DNA (mtDNA)
in amphidiploid plants and studying the genetic interaction between mitochondria and …
in amphidiploid plants and studying the genetic interaction between mitochondria and …
Long-Term Prognosis of Probands With Brugada-Pattern ST-Elevation in Leads V1–V3
…, K Sugi, N Makita, N Hagiwara… - Circulation …, 2009 - Am Heart Assoc
Background— The prognosis of patients with saddleback or noncoved type (non–type 1) ST-elevation
in Brugada syndrome is unknown. The purpose of this study was to clarify the long…
in Brugada syndrome is unknown. The purpose of this study was to clarify the long…