[HTML][HTML] Improvements to the ARTIC multiplex PCR method for SARS-CoV-2 genome sequencing using nanopore

…, H Lapointe, K Kamelian, AD Smith, N Prystajecky… - BioRxiv, 2020 - ncbi.nlm.nih.gov
Genome sequencing has been widely deployed to study the evolution of SARS-CoV-2 with
more than 90,000 genome sequences uploaded to the GISAID database. We published a …

Two-dose SARS-CoV-2 vaccine effectiveness with mixed schedules and extended dosing intervals: test-negative design studies from British Columbia and Quebec …

…, N Prystajecky, JR Tyson, R Gilca, N Brousseau… - MedRxiv, 2021 - medrxiv.org
Background The Canadian COVID-19 immunization strategy deferred second doses and
allowed mixed schedules. We compared two-dose vaccine effectiveness (VE) by vaccine type (…

[HTML][HTML] Real-time PCR-based SARS-CoV-2 detection in Canadian laboratories

…, R McDonald, S Mubareka, N Prystajecky… - Journal of Clinical …, 2020 - Elsevier
… target in the LightMix 2019-nCoV Real-time RT-PCR kit, the RdRp and N gene targets showed
reduced sensitivity. This observation had previously been noted for N gene detection. [17] …

[HTML][HTML] A comparative analysis of current microbial water quality risk assessment and management practices in British Columbia and Ontario, Canada

G Dunn, L Harris, C Cook, N Prystajecky - Science of the Total Environment, 2014 - Elsevier
Bacteria, protozoa and viruses are ubiquitous in aquatic environments and may pose threats
to water quality for both human and ecosystem health. Microbial risk assessment and …

Two-dose severe acute respiratory syndrome coronavirus 2 vaccine effectiveness with mixed schedules and extended dosing intervals: test-negative design studies …

…, M Zou, D Talbot, N Prystajecky… - Clinical Infectious …, 2022 - academic.oup.com
Background The Canadian coronavirus disease 2019 (COVID-19) immunization strategy
deferred second doses and allowed mixed schedules. We compared 2-dose vaccine …

Comparison of approaches to quantify SARS-CoV-2 in wastewater using RT-qPCR: Results and implications from a collaborative inter-laboratory study in Canada

…, MR Mulvey, N Prystajecky, N Srikanthan… - journal of environmental …, 2021 - Elsevier
Prystajecky's group was supported by the BC center for Disease Control, BC center for
Disease Control Foundation for Public Health and Metro Vancouver. The University of Waterloo …

[HTML][HTML] COVID-19 in an immunocompromised host: persistent shedding of viable SARS-CoV-2 and emergence of multiple mutations: a case report

…, GN Al-Rawahi, AN Jassem, N Prystajecky… - International Journal of …, 2022 - Elsevier
This article reports a case of a 21-year-old woman with refractory B-cell acute lymphocytic
leukaemia who presented with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-…

[HTML][HTML] Risk factors for SARS-CoV-2 infection and illness in cats and dogs

…, L Jacobson, S Sparling, N Prystajecky… - Emerging Infectious …, 2022 - ncbi.nlm.nih.gov
… white-tailed deer in Texas and other North America locations had neutralizing antibodies
(22,… suggests SARS-CoV-2 may become endemic in some deer populations in North America. …

[HTML][HTML] A comprehensive method for amplicon-based and metagenomic characterization of viruses, bacteria, and eukaryotes in freshwater samples

…, FSL Brinkman, J Isaac-Renton, NA Prystajecky… - Microbiome, 2016 - Springer
… Black bars represent the mean GCN normalized per nanogram of DNA in each location (n
= 3). Gray bars represent the mean GCN normalized per milliliter of sample (n = 3). Error bars …

Older adults mount less durable humoral responses to two doses of COVID-19 mRNA vaccine but strong initial responses to a third dose

…, JSG Montaner, N Prystajecky… - The Journal of …, 2022 - academic.oup.com
… Our cohort (total n = 151) included 81 health care workers (HCW) and 56 older adults (including
18 residents of long-term care or assisted living facilities) who were COVID-19 naive at …