User profiles for N. Sasai

Noriaki Sasai

Nara Institute of Science and Technology
Verified email at bs.naist.jp
Cited by 4101

[HTML][HTML] Hedgehog signal and genetic disorders

N Sasai, M Toriyama, T Kondo - Frontiers in Genetics, 2019 - frontiersin.org
The hedgehog (Hh) family comprises sonic hedgehog (Shh), Indian hedgehog (Ihh), and
desert hedgehog (Dhh), which are versatile signaling molecules involved in a wide spectrum of …

The role of methyl-binding proteins in chromatin organization and epigenome maintenance

A Fournier, N Sasai, M Nakao… - Briefings in functional …, 2012 - academic.oup.com
… Kaiso is a member of the ZBTB family and contains a BTB/POZ domain at the N terminus
and three tandem Kruppel-like C2H2 zinc fingers at the C terminus. The BTB/POZ domain …

Primary cilia and graded Sonic Hedgehog signaling

N Sasai, J Briscoe - Wiley Interdisciplinary Reviews …, 2012 - Wiley Online Library
Cilia are evolutionary‐conserved microtubule‐containing organelles protruding from the
surface of cells. They are classified into two types—primary and motile cilia. Primary cilia are …

[HTML][HTML] Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube

…, A Ribeiro, J Panovska, E Dessaud, N Sasai… - Cell, 2012 - cell.com
… GFP was first observed in peripheral node cells (n), medial mesoderm (mms) as well as
adjacent ventral mesoderm (ms). Later, GFP expression appeared throughout the ventral part of …

Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells

…, Y Honda, N Sasai, N Yoshimura… - Proceedings of the …, 2005 - National Acad Sciences
… We are grateful to members of the Sasai laboratory for discussion; to S. Nakagawa and H. …
We are grateful to members of the Sasai laboratory for discussion; to S. Nakagawa and H. …

Intrinsic transition of embryonic stem-cell differentiation into neural progenitors

D Kamiya, S Banno, N Sasai, M Ohgushi, H Inomata… - Nature, 2011 - nature.com
n, Temporal expression of Zfp521 during neural differentiation of human ES cells in SFEB
culture. o, Expression levels of Sox3 analysed by qPCR. Human ES cells (lane 1) were …

Requirement of FoxD3-class signaling for neural crest determination in Xenopus

N Sasai, K Mizuseki, Y Sasai - 2001 - journals.biologists.com
Fox factors (winged-helix transcription factors) play important roles in early embryonic
patterning. We show here that FoxD3 (Forkhead 6) regulates neural crest determination in …

Neural crest determination by co-activation of Pax3 and Zic1 genes in Xenopus ectoderm

T Sato, N Sasai, Y Sasai - 2005 - journals.biologists.com
… In this condition, little ectopic expression of the neural marker nrp1 was induced ventrally(n=27), …
We are grateful to members of the Sasai Laboratory for comments on this work, to Drs H. …

[HTML][HTML] Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened

Y Chen, N Sasai, G Ma, T Yue, J Jia, J Briscoe… - PLoS …, 2011 - journals.plos.org
… a dimer/oligomer through an N-terminal interaction(s), which results in high basal FRET
between CFP and YFP fused to the N-termini of two Smo molecules (FRET N ); however, Smo C-…

[HTML][HTML] Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog

…, A Kicheva, BG Novitch, J Briscoe, N Sasai - PLoS …, 2010 - journals.plos.org
Morphogens are secreted signalling molecules that act in a graded manner to control the
pattern of cellular differentiation in developing tissues. An example is Sonic hedgehog (Shh), …