User profiles for N. Shen

Nan Shen

- Verified email at cchmc.org - Cited by 16585

Nan Shen

- Verified email at viome.com - Cited by 5260

Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity

N Shen, T Wang, Q Gan, S Liu, L Wang, B Jin - Food chemistry, 2022 - Elsevier
… R2R3-type MYB TFs are a major group of MYB TFs containing an N-terminal DNA-binding
domain and a C-terminal activation/repression domain, and they play crucial roles in …

The microbiome in early life: implications for health outcomes

S Tamburini, N Shen, HC Wu, JC Clemente - Nature medicine, 2016 - nature.com
Recent studies have characterized how host genetics, prenatal environment and delivery
mode can shape the newborn microbiome at birth. Following this, postnatal factors, such as …

Using oligonucleotide probe arrays to access genetic diversity.

…, M Chee, E Hubbell, MJ Kozal, N Shah, N Shen… - …, 1995 - europepmc.org
As the Human Genome Project and related efforts identify and determine the DNA sequences
of human genes, it is important that highly reliable and efficient mechanisms are found to …

Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome

…, E Robinson, M Mittmann, MS Morris, N Shen… - Science, 1998 - science.org
… (θ can be thought of as twice the number of new mutations per generation arising in a
population with size N e .) Specifically, H ≈ θ and K ≈ θ [1 −1 + 2 −1 + 3 −1 + … + (…

Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21

…, BTN Nguyen, MC Norris, JB Sheehan, N Shen… - Science, 2001 - science.org
… Although a block of N independent biallelic SNPs could in theory generate 2 N different …
of observed haplotypes should be no greater than (N + 1). The complexity of local haplotype …

Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer

MG Dominguez-Bello, KM De Jesus-Laboy, N Shen… - Nature medicine, 2016 - nature.com
… microbiota in mothers that received (n = 13) or did not receive (n = 5) antibiotics before vaginal
… microbiota of mothers that received (n = 13) or did not receive (n = 5) antibiotics before …

Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism

X Wan, B Harkavy, N Shen, P Grohar, LJ Helman - Oncogene, 2007 - nature.com
Rapamycin and several analogs, such as CCI-779 and RAD001, are currently undergoing
clinical evaluation as anticancer agents. In this study, we show that inhibition of mammalian …

Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis

MK Halushka, JB Fan, K Bentley, L Hsie, N Shen… - Nature …, 1999 - nature.com
… All calculations used n=80 and 68 for the Zimbabwe and Tecumseh samples, respectively,
and n=… We acknowledge the assistance of N. Bringht-Twumasi and R. Keefer for technical …

Extensive polymorphisms observed in HIV–1 clade B protease gene using high–density oligonucleotide arrays

MJ Kozal, N Shah, N Shen, R Yang, R Fucini… - Nature medicine, 1996 - nature.com
… Longitudinal samples (n = 65) were available for 53 patients who were drug naive (n = 18)
or RTI experienced (n = 35) and were changed to alternate therapy: zidovudine (AZT) + …

MicroRNA‐146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

…, N de Vries, PP Tak, S Chen, N Shen - … : Official Journal of …, 2009 - Wiley Online Library
… Nan Shen … Nan ShenShen had full access to all of the data in the study and takes
responsibility for the integrity of the data and the accuracy of the data analysis. …