Retrotransposable elements are deleterious at many levels, and the failure of host
surveillance systems for these elements can thus have negative consequences. However, the …

It has been postulated that during human fetal development, all cells of the lung epithelium
derive from embryonic, endodermal, NK2 homeobox 1–expressing (NKX2-1 + ) precursor …

Induced pluripotent stem cells (iPSCs) stand to revolutionize the way we study human
development, model disease, and eventually, treat patients. However, these cell sources produce …

Sickle cell anemia affects millions of people worldwide and is an emerging global health
burden. As part of a large NIH-funded NextGen Consortium, we generated a diverse, …

… For APC detection, 100 μg of protein was loaded on each lane and blotted membranes
were stained with specific antibodies for the N-terminus or C-terminus of APC (S1 Table). …

Retrotransposons are a class of transposable elements capable of self-replication and
insertion into new genomic locations. Across species, the mobilization of retrotransposons in …

… Standard deviations in these panels were previously calculated using the ‘n’ method (‘STDEV.P’
in Microsoft Excel) but we believe the ‘n − 1’ method is more appropriate (‘STDEV.S’ in …

Retrotransposable elements (RTEs) are deleterious at multiple levels, and failure of host
surveillance systems can thus have negative consequences. However, the contribution of RTE …

Manipulation of host phenotypes by parasites is hypothesized to be an adaptive strategy
enhancing parasite transmission across hosts and generations. Characterizing the molecular …

The systemic amyloidoses are diverse disorders in which misfolded proteins are secreted by
effector organs and deposited as proteotoxic aggregates at downstream tissues. Although …