Tumor-infiltrating regulatory T lymphocytes (Treg) can suppress effector T cells specific for
tumor antigens. Deeper molecular definitions of tumor-infiltrating-lymphocytes could thus offer …

… n = 7) and patients with complete donor chimerism (CDC; n = 5) (a) or of healthy adult control
subjects (n … or JAK3 (n = 11) and adult patients with complete donor chimerism (n = 3). (b) …

Understanding the mechanisms that help promote protective immune responses to pathogens
is a major challenge in biomedical research and an important goal for the design of …

… Surprisingly, the DEVD-CHO inhibitor had a higher effect on IETD-dependent protease
activity (3 nm) than on the DEVD-dependent protease activity (15–20 nm). For both tissue …

The world of lymphocytes has recently expanded. A group of cells, innate lymphoid cells (ILC),
has been defined. It includes lymphoid cells that have been known for decades, such as …

As initially demonstrated with murine cytomegalovirus (MCMV), plasmacytoid dendritic cells
(pDCs) are the major source of IFN-α/β in response to a variety of viruses in vivo. However, …

… For this, we treated established tumor (n = 6) and normal (n = 3) colon organoids derived
from nine independent CRC patients with verteporfin (VP), a YAP/TAZ-specific inhibitor that …

… a, Clonal expansion index of CD4 + T cell clusters as designated in the UMAP projection
from n = 2 NSCLC and n = 3 CRC primary tumors shown in Fig. 1a and from n = 2 CRC liver …

Clear cell Renal Cell Carcinoma (ccRCC) is the most common and metastatic urological
cancer. Molecular players of ccRCC progression and metastasis are not completely known. …

Following the discovery of innate immune receptors, the topics of innate immunity and its role
in defense against infective agents have recently blossomed into very active research fields…