Respiratory viral infections are a leading cause of disease and mortality. The severity of these
illnesses can vary markedly from mild or asymptomatic upper airway infections to severe …

Respiratory viral infections, particularly those caused by rhinovirus, exacerbate chronic
respiratory inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (…

Asthma exacerbations are triggered by rhinovirus infections. We employed a systems
biology approach to delineate upper-airway gene network patterns underlying asthma …

RNA-Seq is increasingly used for the diagnosis of patients, targeting of therapies and for
single cell transcriptomics. These applications require cost effective, fast and reliable ways of …

Rationale: No studies have assessed the effects of human rhinovirus (HRV) infection on
epithelial tight junctions (TJs) and resultant barrier function. Aim of the Study: To correlate viral …

Background Asthma is strongly associated with allergic sensitization, but the mechanisms
that determine why only a subset of atopics develop asthma are not well understood. The aim …

Infection-associated inflammatory stress during pregnancy is the most common cause of fetal
growth restriction and/or miscarriage. Treatment strategies for protection of at-risk mothers …

Background Results from recent clinical studies suggest potential efficacy of immune training
(IT)-based approaches for protection against severe lower respiratory tract infections in …

… of 20 nm between 1000 and 1900 nm and 2040 and 2200 nm (a … nm longpass filters,
permitting information from 1100 nm onwards. The 1100 nm filter was then changed to a 1000 nm …

Atopic asthma is a persistent disease characterized by intermittent wheeze and progressive
loss of lung function. The disease is thought to be driven primarily by chronic aeroallergen-…