… in Scotland and New Zealand have demonstrated significant … were substantially greater in
the New Zealand flock [90] in … , with the Romney sheep of New Zealand having minimal skin …

Most common male reproductive disorders are linked to lower testosterone exposure in fetal
life, although the factors responsible for suppressing fetal testosterone remain largely …

Context Aromatase deficiency causes obesity and insulin resistance in aromatase knockout
mice and humans with rare mutations of the aromatase gene (CYP19). Aromatase inhibitors …

Objectives The steroid hormone vitamin D has roles in immunomodulation and bone health.
Insufficiency is associated with susceptibility to respiratory infections. We report 25-hydroxy …

Background Numerous studies in veterinary species have recently linked vitamin D status
with nonskeletal health disorders. Previous studies have indicated that dogs cannot produce …

Acetaminophen (paracetamol‐APAP) is the most common cause of drug‐induced liver
injury in the Western world. Reactive metabolite production by cytochrome P450 enzymes (CYP‐…

Hypovitaminosis D and hypervitaminosis D are well recognised disorders in dogs. Hypovitaminosis
D can occur following consumption of a diet inadequately supplemented with vitamin …

Context: The mechanism of action of metformin remains unclear. Given the regulation of the
cortisol-regenerating enzyme 11βhydroxysteroid dehydrogenase 1 (11βHSD1) by insulin …

… , an industry-recognized simulation software called HOMER Pro ® (hybrid optimization of
multiple electric renewables) is used. The HOMER Pro ® microgrid software has become a …

The assessment of drug-target engagement for determining the efficacy of a compound inside
cells remains challenging, particularly for difficult target proteins. Existing techniques are …