Adaptation is a widespread phenomenon in nervous systems, providing flexibility to function
under varying external conditions. Here, we relate an adaptive property of a sensory system …

We show that the information carried by compound events in neural spike trains—patterns
of spikes across time or across a population of cells—can be measured, independent of …

The capacity of cells and organisms to respond to challenging conditions in a repeatable
manner is limited by a finite repertoire of pre-evolved adaptive responses. Beyond this capacity…

The copy number of any protein fluctuates among cells in a population; characterizing and
understanding these fluctuations is a fundamental problem in biophysics. We show here that …

A key property of neural systems is their ability to adapt selectively to stimuli with different
features. Using multisite electrical recordings from networks of cortical neurons developing ex …

Cells adjust their transcriptional state to accommodate environmental and genetic perturbations.
An open question is to what extent transcriptional response to perturbations has been …

Synaptic plasticity – the directed modulation of synaptic connections by specific activity
histories or physiological signals – is believed to be a major mechanism for the modification of …

What is the physiological basis of long-term memory? The prevailing view in Neuroscience
attributes changes in synaptic efficacy to memory acquisition, implying that stable memories …

Microbial growth and division are fundamental processes relevant to many areas of life
science. Of particular interest are homeostasis mechanisms, which buffer growth and division …

Long-term, repeated measurements of individual synaptic properties have revealed that
synapses can undergo significant directed and spontaneous changes over time scales of …