Oral Diseases (2011) 17, 345–354 For the past two decades, salivary diagnostic approaches
have been developed to monitor oral diseases such as periodontal diseases and to assess …

Recent studies have demonstrated that discriminatory salivary biomarkers can be readily
detected upon the development of systemic diseases such as pancreatic cancer, breast cancer…

Early detection of oral squamous cell cancer (OSCC) is the key to improve the low 5-year
survival rate. Using proteomic and genomic technologies we have previously discovered and …

Mouse models are a critical tool for studying human diseases, particularly developmental
disorders 1 . However, conventional approaches for phenotyping may fail to detect subtle …

Cortical spreading depression (CSD), a wave of depolarization followed by depression of
cortical activity, is a pathophysiological process implicated in migraine with aura and various …

Current concepts regarding the biology of aging are primarily based on studies aimed at
identifying factors regulating lifespan. However, lifespan as a sole proxy measure for aging can …

Clinical presentation of congenital heart disease is heterogeneous, making identification of
the disease-causing genes and their genetic pathways and mechanisms of action …

BACKGROUND Evaluation of the salivary transcriptome is an emerging diagnostic technology
with discriminatory power for disease detection. This study explored massively parallel …

The genetic landscape of diseases associated with changes in bone mineral density (BMD),
such as osteoporosis, is only partially understood. Here, we explored data from 3,823 …

Adenosine (Ado) mediates vasoconstriction via A 1 -Ado receptors and vasodilation via A 2 -Ado
receptors in the kidney. It interacts with angiotensin II (Ang II), which is important for …