The use of neural stem cell (NSC) therapy for the treatment of stroke patients is successfully
paving its way into advanced phases of large-scale clinical trials. To understand how to …

Stem cell therapies demonstrate promising results as treatment for neurological disease
and injury, owing to their innate ability to enhance endogenous neural tissue repair and …

Purpose of Review Considerable progress has been made in the field of stem cell research;
nonetheless, the use of stem cells for regenerative medicine therapies, for either …

Endothelial cell migration, proliferation and survival are triggered by VEGF-A activation of
VEGFR2. However, how these cell behaviors are regulated individually is still unknown. Here …

During blood vessel development, endothelial cells become specified toward arterial or
venous fates to generate a circulatory network that provides nutrients and oxygen to, and …

Serotonin (5-HT) is a potent vasoconstrictor agonist and contributes to several vascular
diseases including systemic or pulmonary hypertension and atherosclerosis. Although …

The mechanisms underlying pulmonary hypertension (PH) are complex and multifactorial,
and involve different cell types that are interconnected through gap junctional channels. …

… In this study, Genet et al. describe the role of the gap junction protein connexin 43 in the
adult brain subventricular zone where neural stem cells (NSCs) reside. Genet al. show that …

BACKGROUND: Distinct endothelial cell cycle states (early G1 versus late G1) provide
different “windows of opportunity” to enable the differential expression of genes that regulate …

… Nafiisha Genet1,2 & Neha Bhatt1,2 & Antonin Bourdieu1,2 & Karen K. Hirschi1,2 … 1
Department of Medicine, Genetics and Biomedical Engineering, Yale Cardiovascular …