User profiles for Nagarjuna Reddy Pamudurti

Nagarjuna Pamudurti

Brandeis university
Verified email at mail.huji.ac.il
Cited by 4399

[PDF][PDF] circRNA biogenesis competes with pre-mRNA splicing

R Ashwal-Fluss, M Meyer, NR Pamudurti, A Ivanov… - Molecular cell, 2014 - cell.com
Circular RNAs (circRNAs) are widely expressed noncoding RNAs. However, their biogenesis
and possible functions are poorly understood. Here, by studying circRNAs that we …

[PDF][PDF] Translation of circRNAs

NR Pamudurti, O Bartok, M Jens, R Ashwal-Fluss… - Molecular cell, 2017 - cell.com
Circular RNAs (circRNAs) are abundant and evolutionarily conserved RNAs of largely
unknown function. Here, we show that a subset of circRNAs is translated in vivo. By performing …

[PDF][PDF] circMbl functions in cis and in trans to regulate gene expression and physiology in a tissue-specific fashion

NR Pamudurti, IL Patop, A Krishnamoorthy, O Bartok… - Cell reports, 2022 - cell.com
Muscleblind (mbl) is an essential muscle and neuronal splicing regulator. Mbl hosts multiple
circular RNAs (circRNAs), including circMbl, which is conserved from flies to humans. Here, …

SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome

M Zaffagni, JM Harris, IL Patop, NR Pamudurti… - Elife, 2022 - elifesciences.org
Viral infection involves complex set of events orchestrated by multiple viral proteins. To
identify functions of SARS-CoV-2 proteins, we performed transcriptomic analyses of cells …

[HTML][HTML] An in vivo strategy for knockdown of circular RNAs

NR Pamudurti, IL Patop, A Krishnamoorthy… - Cell discovery, 2020 - nature.com
Exonic circular RNAs (circRNAs) are highly abundant RNAs generated mostly from exons of
protein-coding genes. Assaying the functions of circRNAs is not straightforward as common …

An in vivo knockdown strategy reveals multiple functions for circMbl

NR Pamudurti, VV Konakondla-Jacob… - bioRxiv, 2018 - biorxiv.org
Circular RNAs (circRNAs) are highly abundant and evolutionary conserved RNAs of mostly
unknown functions. circRNAs are enriched in the brain and accumulate with age in flies, …

[PDF][PDF] An in vivo strategy for knockdown of circular RNAs

PN Reddy, IL Patop, K Aishwarya, AF Reut… - Cell …, 2020 - drive.google.com
Exonic circular RNAs (circRNAs) are highly abundant RNAs generated mostly from exons of
protein-coding genes. Assaying the functions of circRNAs is not straightforward as common …

circMbl Functions in cis and in trans to Regulate Gene Expression With Impacts on Physiology

NR Pamudurti, I Patop, A Krishnamoorthy… - Available at SSRN … - papers.ssrn.com
Muscleblind (mbl) is an essential muscle and neuronal splicing regulator and the causative
agent of myotonic dystrophy. Mbl hosts an abundant circular RNA, circMbl, which is …

SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome (preprint)

M Zaffagni, JM Harris, IL Patop, NR Pamudurti… - 2021 - pesquisa.bvsalud.org
To identify functions of SARS-CoV-2 proteins, we performed transcriptomic analyses of cells
expressing individual viral proteins. Expression of Nsp14, a protein involved in viral RNA …

Investigation of cap-independent translation in neuronal differentiation

L Ruhe - 2020 - edoc.hu-berlin.de
Translation initiation is a complex and highly regulated process which involves the assembly
of an elongation competent ribosome on the mRNA. The vast majority of eukaryotic mRNAs …