The vast amount of RNA-seq data deposited in Gene Expression Omnibus (GEO) and Sequence
Read Archive (SRA) is still a grossly underutilized resource for biomedical research. To …

In the connectivity map (CMap) approach to drug repositioning and development, transcriptional
signature of disease is constructed by differential gene expression analysis between …

Importance Coronavirus disease 2019 (COVID-19) outbreaks are frequent occurrences in
nursing homes and long-term care facilities (LTCFs), resulting in subsequent hospitalization …

One of the main objectives of many biological studies is to explore differential gene expression
profiles between samples. Genes are referred to as differentially expressed (DE) if the …

Background and Aims This study assessed whether baseline triggering receptor expressed
on myeloid cells [TREM-1] whole blood gene expression predicts response to anti-tumour …

… The Genes pipeline allows users to input a gene set of interest, and then to select a LINCS
or non-LINCS dataset and signatures to query, analyze, and visualize. The Datasets pipeline …

One of the primary objectives of ribonucleic acid (RNA) sequencing or RNA-Seq experiment
is to identify differentially expressed (DE) genes in two or more treatment conditions. It is a …

With the recent progress in high-throughput sequencing technologies, unprecedented amount
of data from multiple omics modalities including genomics, transcriptomics, proteomics, …

The Library of Integrated Network-based Cellular Signatures (LINCS) program is a national
consortium funded by the NIH to generate a diverse and extensive reference library of cell-…

Lymphangioleiomyomatosis (LAM) is a rare pulmonary disease affecting women of childbearing
age that is characterized by the aberrant proliferation of smooth-muscle (SM)-like cells …