User profiles for Nakul Ravi Raval
 | Nakul Ravi RavalYale University Verified email at yale.edu Cited by 213 |
[HTML][HTML] A single dose of psilocybin increases synaptic density and decreases 5-HT2A receptor density in the pig brain
NR Raval, A Johansen, LL Donovan, NF Ros… - International journal of …, 2021 - mdpi.com
A single dose of psilocybin, a psychedelic and serotonin 2A receptor (5-HT 2A R) agonist,
may be associated with antidepressant effects. The mechanism behind its antidepressive …
may be associated with antidepressant effects. The mechanism behind its antidepressive …
[HTML][HTML] Pretargeted imaging beyond the blood–brain barrier
…, IV Andersen, RG Vázquez, NR Raval… - RSC medicinal …, 2023 - pubs.rsc.org
Pretargeting is a powerful nuclear imaging strategy to achieve enhanced imaging contrast
for nanomedicines and reduce the radiation burden to healthy tissue. Pretargeting is based …
for nanomedicines and reduce the radiation burden to healthy tissue. Pretargeting is based …
[HTML][HTML] Synaptic density and neuronal metabolic function measured by positron emission tomography in the unilateral 6-OHDA rat model of Parkinson's disease
Parkinson’s disease (PD) is caused by progressive neurodegeneration and characterised
by motor dysfunction. Neurodegeneration of dopaminergic neurons also causes aberrations …
by motor dysfunction. Neurodegeneration of dopaminergic neurons also causes aberrations …
[HTML][HTML] Evaluation of the α-synuclein PET radiotracer (d3)-[11C] MODAG-001 in pigs
NR Raval, CA Madsen, V Shalgunov, A Nasser… - Nuclear Medicine and …, 2022 - Elsevier
Background A positron emission tomography (PET) radiotracer to neuroimage α-synuclein
aggregates would be a crucial addition for early diagnosis and treatment development in …
aggregates would be a crucial addition for early diagnosis and treatment development in …
Kinetic models for estimating occupancy from single-scan PET displacement studies
…, A Johansen, NR Raval… - Journal of Cerebral …, 2023 - journals.sagepub.com
The traditional design of PET target engagement studies is based on a baseline scan and
one or more scans after drug administration. We here evaluate an alternative design in which …
one or more scans after drug administration. We here evaluate an alternative design in which …
[HTML][HTML] An in vivo Pig Model for Testing Novel Positron Emission Tomography Radioligands Targeting Cerebral Protein Aggregates
NR Raval, A Nasser, CA Madsen… - Frontiers in …, 2022 - frontiersin.org
Positron emission tomography (PET) has become an essential clinical tool for diagnosing
neurodegenerative diseases with abnormal accumulation of proteins like amyloid-β or tau. …
neurodegenerative diseases with abnormal accumulation of proteins like amyloid-β or tau. …
An in vivo pig model for testing novel PET radioligands targeting cerebral protein aggregates
NR Raval, A Nasser, CA Madsen, N Beschorner… - bioRxiv, 2022 - biorxiv.org
Positron emission tomography (PET) has become an essential clinical tool for diagnosing
neurodegenerative diseases with abnormal accumulation of proteins like amyloid-β or tau. …
neurodegenerative diseases with abnormal accumulation of proteins like amyloid-β or tau. …
Synaptic density and neuronal metabolic function measured by PET in the unilateral 6-OHDA rat model of Parkinson's disease
Parkinson’s disease (PD) is caused by progressive neurodegeneration and characterised
by motor dysfunction. Neurodegeneration of dopaminergic neurons also causes aberrations …
by motor dysfunction. Neurodegeneration of dopaminergic neurons also causes aberrations …
Kinetic models for PET displacement studies
The traditional design of PET target engagement studies is based on a baseline scan and
one or more scans after drug administration. We here evaluate an alternative design in which …
one or more scans after drug administration. We here evaluate an alternative design in which …
A single dose of psilocybin increases synaptic density and decreases 5-HT2A receptor density in the pig brain
NR Raval, A Johansen, LL Donovan, NF Ros… - 2020 - preprints.org
A single dose of psilocybin, a psychedelic and serotonin 2A receptor (5-HT2AR) agonist,
may be associated with antidepressant effects. The mechanism behind its antidepressive …
may be associated with antidepressant effects. The mechanism behind its antidepressive …