The taste receptor type 1 (T1r) family perceives ‘palatable’ tastes. These receptors function
as T1r2-T1r3 and T1r1-T1r3 heterodimers to recognize a wide array of sweet and umami (…

Sweet and umami tastes are perceived by T1r taste receptors in oral cavity. T1rs are class C
G-protein coupled receptors (GPCRs), and the extracellular ligand binding domains (LBDs) …

Salt taste sensation is multifaceted: NaCl at low or high concentrations is preferably or
aversively perceived through distinct pathways. Cl− is thought to participate in taste sensation …

Cortisol-producing adrenocortical adenomas (CPAs) are associated with ACTH-independent
Cushing’s syndrome and histologically composed of two cellular subtypes: compact (lipid-…

Background While previous studies indicate that the zonae reticularis (ZR) and glomerulosa
(ZG) diminish with aging, little is known about age-related transformations of the zona …

Background: Previous adrenal morphological studies have shown that the zona reticularis (ZR)
and the zona glomerulosa (ZG) decrease in size with aging. Although several lines of …

Diazinon is an organophosphorus (OP) insecticide and is widely used not only in agriculture
but also homes and garden in Japan. Diazinon has been reported to increase TNF-α …

Purpose The purpose of this study was to clarify the usefulness of indocyanine green
fluorescence imaging (ICG-FI) in the assessment of intestinal vascular perfusion in patients who …

Neonicotinoid insecticides and organophosphorus (OP) insecticides that act on the cholinergic
nervous system of insects, are major insecticides used in agriculture throughout the world…

Artificial phase-separating (PS) peptides can be used in various applications such as
microreactors and drug delivery; however, the design of artificial PS peptides remains a challenge. …