Background & Aims: We evaluated etanercept, a human soluble tumor necrosis factor
receptor: Fc fusion protein, for the treatment of active Crohn's disease. Methods: Forty-three …

Background & Aims: To determine accuracy of endoscopic ultrasound (EUS) and magnetic
resonance imaging (MRI) for evaluation of Crohn's disease perianal fistulas. Methods: Thirty-…

Purpose: To develop a single TBI severity classification system based on commonly used
TBI severity measures and indicators that (1) maximally uses available positive evidence to …

PURPOSE: To determine the incidence of central serous chorioretinopathy (CSC) in Olmsted
County, Minnesota from 1980 to 2002, determine the associated risk factors for CSC based …

OBJECTIVE: To determine the incidence and types of childhood exotropia in a defined
population. DESIGN: Retrospective, population-based cohort. PARTICIPANTS: All pediatric (<19 …

PURPOSE: To determine the incidence of full-thickness macular holes in Olmsted County,
Minnesota. DESIGN: Population-based retrospective chart review (cross-sectional study). …

Background Background The leucine-rich repeat kinase 2 gene (LRRK2) harbours highly
penetrant mutations that are linked to familial parkinsonism. However, the extent of its …

Background Hexanucleotide repeat expansions in chromosome 9 open reading frame 72 (C9ORF72)
are the most common known genetic cause of frontotemporal dementia (FTD) and …

OBJECTIVE: To describe the incidence and types of childhood esotropia in a defined
population. DESIGN: Retrospective population-based cohort. PARTICIPANTS: All pediatric (<19 …

There is no effective treatment for amyotrophic lateral sclerosis (ALS), a devastating motor
neuron disease. However, discovery of a G 4 C 2 repeat expansion in the C9ORF72 gene as …