User profiles for Nancy Papalopulu

Nancy Papalopulu

Professor of Developmental Neuroscience
Verified email at manchester.ac.uk
Cited by 8006

The murine and Drosophila homeobox gene complexes have common features of organization and expression

A Graham, N Papalopulu, R Krumlauf - Cell, 1989 - cell.com
In situ hybridization analysis of mouse embryos shows the seven members of the Hex-2
complex to be differentially expressed in the central and peripheral nervous system and in …

microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons

…, P Garcez, P Stanley, F Guillemot, N Papalopulu - Nature …, 2012 - nature.com
The capacity of neurons to develop a long axon and multiple dendrites defines neuron
connectivity in the CNS. The highly conserved microRNA-9 (miR-9) is expressed in both neuronal …

Downregulation of Par3 and aPKC function directs cells towards the ICM in the preimplantation mouse embryo

…, CA Moore, N Papalopulu… - Journal of cell …, 2005 - journals.biologists.com
Generation of inside cells that develop into inner cell mass (ICM) and outside cells that
develop into trophectoderm is central to the development of the early mouse embryo. Critical to …

Techniques and probes for the study of Xenopus tropicalis development

…, N Taverner, E Amaya, N Papalopulu… - … dynamics: an official …, 2002 - Wiley Online Library
The frog Xenopus laevis has provided significant insights into developmental and cellular
processes. However, X. laevis has an allotetraploid genome precluding its use in forward …

An essential role for retinoid signaling in anteroposterior neural patterning

…, C Kintner, RM Evans, N Papalopulu - …, 1997 - journals.biologists.com
The vertebrate central nervous system (CNS) is induced by signals emanating from the dorsal
mesoderm, or organizer, that divert the ectoderm away from an epidermal and towards a …

[PDF][PDF] MicroRNA-9 modulates Hes1 ultradian oscillations by forming a double-negative feedback loop

B Bonev, P Stanley, N Papalopulu - Cell reports, 2012 - cell.com
Short-period (ultradian) oscillations of Hes1, a Notch signaling effector, are essential for
maintaining neural progenitors in a proliferative state, while constitutive downregulation of Hes1 …

[PDF][PDF] MicroRNA-9 reveals regional diversity of neural progenitors along the anterior-posterior axis

B Bonev, A Pisco, N Papalopulu - Developmental cell, 2011 - cell.com
Neural progenitors self-renew and generate neurons throughout the central nervous system.
Here, we uncover an unexpected regional specificity in the properties of neural progenitor …

[PDF][PDF] Integration of telencephalic Wnt and hedgehog signaling center activities by Foxg1

…, M Johansson, V Snowden, A Cording, N Papalopulu… - Developmental cell, 2009 - cell.com
The forebrain is patterned along the dorsoventral (DV) axis by Sonic Hedgehog (Shh). However,
previous studies have suggested the presence of an Shh-independent mechanism. Our …

[HTML][HTML] Xiro3 encodes a Xenopus homolog of the Drosophila Iroquois genes and functions in neural specification

…, P Gruss, T Pieler, JB Gurdon, N Papalopulu - The EMBO …, 1998 - embopress.org
We have identified in Xenopus and in the mouse two highly related genes, Xiro3 and Irx3
respectively, that encode a Drosophila Iroquois‐related homeobox transcription factor. Xiro3 in …

Expression of Pax-3 in the lateral neural plate is dependent on a Wnt-mediated signal from posterior nonaxial mesoderm

AG Bang, N Papalopulu, MD Goulding, C Kintner - Developmental biology, 1999 - Elsevier
During early patterning of the vertebrate neuraxis, the expression of the paired-domain
transcription factor Pax-3 is induced in the lateral portions of the posterior neural plate via …