S phase specific formation of the human Rad51 protein nuclear foci in lymphocytes.

S Tashiro, N Kotomura, A Shinohara, K Tanaka… - Oncogene, 1996 - europepmc.org
The Rad51 protein, which is a homologue of the bacterial RecA protein, is involved in mitotic
and meiotic recombination and in repair of double-strand breaks of DNA in yeast. The …

Novel nucleosomal particles containing core histones and linker DNA but no histone H1

…, T Nikitina, V Nagarajavel, N Kotomura… - Nucleic acids …, 2016 - academic.oup.com
Eukaryotic chromosomal DNA is assembled into regularly spaced nucleosomes, which play
a central role in gene regulation by determining accessibility of control regions. The …

Local states of chromatin compaction at transcription start sites control transcription levels

…, H Yamashita, M Umeda, N Kotomura… - Nucleic acids …, 2021 - academic.oup.com
The ‘open’ and ‘compact’ regions of chromatin are considered to be regions of active and
silent transcription, respectively. However, individual genes produce transcripts at different …

Complex cell cycle abnormalities caused by human T-lymphotropic virus type 1 Tax

L Yang, N Kotomura, YK Ho, H Zhi, S Bixler… - Journal of …, 2011 - Am Soc Microbiol
Human T-lymphotropic virus type 1 (HTLV-1) is the causative agent of adult T-cell leukemia/lymphoma
(ATL), a malignancy of CD4 + T cells whose etiology is thought to be associated …

Genomic organization and isoforms of the mouse ELP gene

Y Ninomiya, M Okada, N Kotomura… - The journal of …, 1995 - academic.oup.com
Abstract Analysis was made on the genomic structure, functions, and expression of the mouse
ELP gene, which codes for the embryonal long terminal repeat binding protein. Extensive …

Identification of novel first exons in Ad4BP/SF-1 (NR5A1) gene and their tissue-and species-specific usage

R Kimura, H Yoshii, M Nomura, N Kotomura… - Biochemical and …, 2000 - Elsevier
It has been demonstrated that the mammalian Ad4BP/SF-1 (NR5A1) gene is regulated
precisely in sex, tissue, and developmental stage specific manners. To clarify the complex …

Identification of illegitimate recombination hot spot of the retinoic acid receptor alpha gene involved in 15; 17 chromosomal translocation of acute promyelocytic …

S Tashiro, N Kotomura, K Tanaka, K Suzuki, T Kyo… - Oncogene, 1994 - europepmc.org
Acute promyelocytic leukemia (APL) has been characterized by 15; 17 chromosomal translocation,
which involves the retinoic acid receptor alpha (RARA) gene on chromosome 17 and …

Overproduction of Biologically-active Human Nerve Growth Factor in Escherichia coli

K Fujimori, S Fukuzono, N Kotomura… - Bioscience …, 1992 - Taylor & Francis
A gene coding for human nerve growth factor (hNGF) was constructed for expression under
control of the trp promoter in E. coli. The plasmid pTRSNGF contained a synthetic hNGF …

Association of Minisatellite Instability with c-myc Amplification and K-ras Mutation in Methylcholanthrene-induced Mouse Sarcomas

…, Y Nitta, Z Wang, YJ Fan, Y Ninomiya, N Kotomura… - Cancer research, 1995 - AACR
Instability of microsatellite sequences are frequently found in human tumors. In addition,
minisatellite sequences, another group of highly unstable sequences, serve as sensitive …

Sfh1, an essential component of the RSC chromatin remodeling complex, maintains genome integrity in fission yeast

N Kotomura, S Tsunemine, M Kuragano… - Genes to …, 2018 - Wiley Online Library
Abp1 is a fission yeast CENP ‐B homologue that contributes to centromere function, silencing
at pericentromeric heterochromatin and silencing of retrotransposons. We identified the …