Objectives To describe and examine trends in polypharmacy according to age in Japan
from 2010 to 2016. Design Retrospective observational study. Setting Outpatient settings. …

Dementia is a major public health concern in ageing societies. Although the population of
Japan is among the most aged worldwide, long-term trends in the place of death (PoD) among …

New series of ferroelectric liquid crystals with two chiral carbons or bulky molecular
components at the chiral carbon are synthesized and are found to possess extremely large …

Background In this age of antimicrobial resistance, unnecessary use of antibiotics to treat
non-bacterial acute respiratory tract infections (ARTIs) and inappropriate use of antibiotics in …

Background: Globally, the number of deaths is estimated to increase to 74 million per year by
2030. Place of death (PoD) is increasingly being recognized as an important aspect of end-…

A new type of ferroelectric liquid crystal, the 4′-alkoxybiphenyl-4-yl (2S,3S)-3-methyl-2-halogenopentanoates,
has been synthesized; these compounds possess novel ferroelectricity, …

New series of ferroelectric liquid crystals with neighbouring chiral carbons or a chiral carbon
with C—CI binding next to the molecular dipole moment (C=O) are synthesized utilizing …

Electro-optic effects in newly synthesized ferroelectric liquid crystals (2S, 3S)-3-methyl-2-halopentanoic
acid 4', 4''-alkoxybiphenyl ester have been studied and it is clarified that these …

In ferroelectric liquid crystals of biphenyl ester series with alkylcarbonyloxy (C n H 2n+ 1
COO) chain length n longer than 9 exhibit anomalous dielectric behaviour. The spontaneous …

The anomalous voltage-transmission hysteresis of ferroelectric liquid crystals associated
with the unwinding and winding of a helicoidal structure was studied in detail. Utilizing this …