An atlas of active enhancers across human cell types and tissues
Enhancers control the correct temporal and cell-type-specific activation of gene expression
in multicellular eukaryotes. Knowing their properties, regulatory activity and targets is crucial …
in multicellular eukaryotes. Knowing their properties, regulatory activity and targets is crucial …
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells
…, Y Ishizu, M Itoh, T Kawashima, M Kojima, N Kondo… - Science, 2015 - science.org
Although it is generally accepted that cellular differentiation requires changes to transcriptional
networks, dynamic regulation of promoters and enhancers at specific sets of genes has …
networks, dynamic regulation of promoters and enhancers at specific sets of genes has …
MiR-206 expression is down-regulated in estrogen receptor α–positive human breast cancer
N Kondo, T Toyama, H Sugiura, Y Fujii, H Yamashita - Cancer research, 2008 - AACR
Expression levels of estrogen receptor (ER) α govern estrogen-dependent growth, response
to endocrine therapy, and prognosis in ERα-positive breast cancer. Multiple mechanisms …
to endocrine therapy, and prognosis in ERα-positive breast cancer. Multiple mechanisms …
Treatment outcomes and prognostic factors for patients with brain metastases from breast cancer of each subtype: a multicenter retrospective analysis
…, M Ishida, Y Hozumi, M Tsuneizumi, N Kondo… - Breast cancer research …, 2014 - Springer
To define prognostic factors for breast cancer patients with brain metastases, compare their
clinical courses and prognoses according to breast cancer subtypes, and analyze the …
clinical courses and prognoses according to breast cancer subtypes, and analyze the …
Cadystin a and b, major unit peptides comprising cadmium binding peptides induced in a fission yeast-----separation, revision of structures and synthesis
N Kondo, K Imai, M Isobe, T Goto, A Murasugi… - Tetrahedron …, 1984 - Elsevier
The unit peptide, cadystin, of the cadmium-binding peptides occurring in a fission yeast was
further separated into two major components, cadystin A and B, structures of which were …
further separated into two major components, cadystin A and B, structures of which were …
Functional annotation of human long noncoding RNAs via molecular phenotyping
…, T Kawashima, ST Kelly, M Kojima, N Kondo… - Genome …, 2020 - genome.cshlp.org
Long noncoding RNAs (lncRNAs) constitute the majority of transcripts in the mammalian
genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project, we …
genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project, we …
Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation
…, M Kojima, S Kojima, N Kondo… - Proceedings of the …, 2014 - National Acad Sciences
Naturally occurring regulatory T (Treg) cells, which specifically express the transcription
factor forkhead box P3 (Foxp3), are engaged in the maintenance of immunological self-…
factor forkhead box P3 (Foxp3), are engaged in the maintenance of immunological self-…
High expression of microRNA-210 is an independent factor indicating a poor prognosis in Japanese triple-negative breast cancer patients
T Toyama, N Kondo, Y Endo, H Sugiura… - Japanese journal of …, 2012 - academic.oup.com
Objective MicroRNAs have emerged as a new class of non-coding genes involved in regulating
cell proliferation, differentiation and viability. Recent studies have identified miR-210 as …
cell proliferation, differentiation and viability. Recent studies have identified miR-210 as …
[HTML][HTML] Comparison of clinical outcomes between luminal invasive ductal carcinoma and luminal invasive lobular carcinoma
…, M Ichikawa, N Gondo, A Yoshimura, N Kondo… - BMC cancer, 2016 - Springer
Background The pathological and clinical features of invasive lobular carcinoma (ILC) differ
from those of invasive ductal carcinoma (IDC). Several studies have indicated that patients …
from those of invasive ductal carcinoma (IDC). Several studies have indicated that patients …
[HTML][HTML] Development of a new rapid isolation device for circulating tumor cells (CTCs) using 3D palladium filter and its application for genetic analysis
…, T Masuda, S Ito, S Yamamoto, M Okochi, N Kondo… - PloS one, 2014 - journals.plos.org
Circulating tumor cells (CTCs) in the blood of patients with epithelial malignancies provide a
promising and minimally invasive source for early detection of metastasis, monitoring of …
promising and minimally invasive source for early detection of metastasis, monitoring of …