User profiles for Narayan Dahal

Narayan Dahal

- Verified email at duke.edu - Cited by 160

Narayan Prasad Dahal

- Verified email at nou.edu.np - Cited by 2

Molecular basis for ADP-ribose binding to the Mac1 domain of SARS-CoV-2 nsp3

DN Frick, RS Virdi, N Vuksanovic, N Dahal… - Biochemistry, 2020 - ACS Publications
The virus that causes COVID-19, SARS-CoV-2, has a large RNA genome that encodes
numerous proteins that might be targets for antiviral drugs. Some of these proteins, such as the …

Binding-induced stabilization measured on the same molecular protein substrate using single-molecule magnetic tweezers and heterocovalent attachments

N Dahal, J Nowitzke, A Eis, I Popa - The Journal of Physical …, 2020 - ACS Publications
Binding-induced mechanical stabilization plays key roles in proteins involved in muscle
contraction, cellular mechanotransduction, or bacterial adhesion. Because of the vector nature of …

Mechanical regulation of talin through binding and history-dependent unfolding

N Dahal, S Sharma, B Phan, A Eis, I Popa - Science Advances, 2022 - science.org
Talin is a force-sensing multidomain protein and a major player in cellular mechanotransduction.
Here, we use single-molecule magnetic tweezers to investigate the mechanical …

Force-clamp rheometry for characterizing protein-based hydrogels

LR Khoury, J Nowitzke, N Dahal, K Shmilovich… - JoVE (Journal of …, 2018 - jove.com
Here, we describe a force-clamp rheometry method to characterize the biomechanical
properties of protein-based hydrogels. This method uses an analog proportional-integral-…

[PDF][PDF] A comparative analysis of prediction of student results using decision trees and random forest

NP Dahal, S Shakya - Journal of Trends in Computer Science and …, 2022 - academia.edu
Many types of research are based on students' past data for predicting their performance. A
lot of data mining techniques for analyzing the data have been used so far. This research …

Mechanical reinforcement of protein L from Finegoldia magna points to a new bind-and-search mechanism

NR Dahal, J Nowitzke, A Eis, I Popa - bioRxiv, 2019 - biorxiv.org
Several significant bacterial pathogens in humans secrete surface proteins that bind antibodies
in order to protect themselves from the adaptive immune response and have evolved to …

[PDF][PDF] An Analysis of Prediction of Students' Results Using Deep Learning

NP Dahal, S Shakya - Computing Open, 2023 - researchgate.net
Many eŽorts have already been carried out for education mining in the past. Many techniques
and models are already developed to predict and identify students' performance, learning …

[PDF][PDF] Variable Macro X Domain of SARS-CoV-2 Retains the Ability to Bind ADP-ribose

DN Frick, RS Virdi, N Vuksanovic, N Dahal… - bioRxiv, 2020 - academia.edu
The virus that causes COVID-19, SARS-CoV-2, has a large RNA genome that encodes
numerous proteins that might be targets for antiviral drugs. Some of these proteins, such as the …

[PDF][PDF] History dependent mechanical response of talin and its interaction to DLC1

N Dahal, S Sharma, B Phan, A Eis, I Popa - Biophysical Journal, 2022 - cell.com
Proteins operating under force are involved in several biological processes and perform
multiple roles. Talin is one such force-sensing multidomain protein which act as a major player …